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Substance-K receptor
Summary
- UniProt ID
- P16610
- Gene Symbol
- Tac2r Tacr2
- Gene ID
- 25007
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Palmitate Reference proteome Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| adenylate cyclase-activating G protein-coupled receptor signaling pathway | ||
| phospholipase C-activating tachykinin receptor signaling pathway | ||
| positive regulation of acetylcholine secretion, neurotransmission | ||
| intestine smooth muscle contraction | ||
| negative regulation of luteinizing hormone secretion |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| sperm flagellum |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| substance K receptor activity | ||
| substance K receptor activity | ||
| substance K receptor activity | ||
| substance K receptor activity |
GO Hierarchy
Sequence
MGTRAIVSDANILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAIIAGIWLVALALASPQCFYSTITVDEGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTHTPSLSRRVNRCHTKETLFMTGDMTHSEATNGQVGSPQDGEPAGPICKAQA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 19 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (q) signalling events | Rattus norvegicus |
| Tachykinin receptors bind tachykinins | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:6432 | pulmonary hypertension | |
| DOID:0060180 | colitis |
