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Hepatocyte growth factor

Summary

UniProt ID

P17945

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P17945

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Growth factor
Kringle
Pyrrolidone carboxylic acid
Reference proteome
Repeat
Serine protease homolog
Signal

Gene Ontology (GO)

Displaying entries **11 - 20** of 30 in total

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GO Term
positive regulation of angiogenesis
epithelial cell proliferation
negative regulation of inflammatory response
skeletal muscle cell proliferation
animal organ regeneration
positive regulation of myelination
negative regulation of interleukin-6 production
positive regulation of interleukin-10 production
negative regulation of apoptotic process
positive regulation of peptidyl-tyrosine phosphorylation

Displaying 1 entry
GO Term
extracellular space

Displaying **all 5** entries
GO Term
growth factor activity
chemoattractant activity
signaling receptor binding
protein-containing complex binding
identical protein binding

Annotation information from UniProt.

Sequence

MMWGTKLLPVLLLQHVLLHLLLLPVTIPYAEGQKKRRNTLHEFKKSAKTTLTKEDPLVKIKTKKVNSADECANRCIRNKGFPFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEFDLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSAVNETDVPMETTECIKGQGEGYRGTTNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNMEDLHRHIFWEPDASKLTKNYCRNPDDDAHGPWCYTGNPLVPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTQTTVGWMVSLKYRNKHICGGSLIKESWVLTARQCFPARNKDLKDYEAWLGIHDVHERGEEKRKQILNISQLVYGPEGSDLVLLKLARPAILDNFVSTIDLPSYGCTIPEKTTCSIYGWGYTGLINADGLLRVAHLYIMGNEKCSQHHQGKVTLNESELCAGAEKIGSGPCEGDYGGPLICEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKVILTYKL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
295	N-linked (GlcNAc...) asparagine	UniProt
403	N-linked (GlcNAc...) asparagine	UniProt
569	N-linked (GlcNAc...) asparagine	UniProt
656	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 15** of 15 in total

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Pathway Name	Organism
Negative regulation of MET activity	Rattus norvegicus
PI3K/AKT Signaling	Rattus norvegicus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Rattus norvegicus
Platelet degranulation	Rattus norvegicus
RAF/MAP kinase cascade	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements