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Alpha-2A adrenergic receptor

Summary

UniProt ID

P18871

Gene Symbol

A2AR
ADRA2A

Gene ID

399501

Organism

Sus scrofa (pig)

External Links

PubChem: P18871
Re-Glyco: P18871

Annotation

Keyword

Cell membrane
Direct protein sequencing
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
plasma membrane
receptor complex
presynapse
dopaminergic synapse
cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 23 in total

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GO Term
presynaptic modulation of chemical synaptic transmission
positive regulation of cytokine production
cellular response to hormone stimulus
positive regulation of potassium ion transport
positive regulation of MAPK cascade
regulation of vasoconstriction
positive regulation of epidermal growth factor receptor signaling pathway
negative regulation of lipid catabolic process
positive regulation of membrane protein ectodomain proteolysis
adenylate cyclase-activating adrenergic receptor signaling pathway

Displaying **all 10** entries
GO Term
alpha2-adrenergic receptor activity
alpha-1B adrenergic receptor binding
alpha-2C adrenergic receptor binding
thioesterase binding
heterotrimeric G-protein binding
epinephrine binding
norepinephrine binding
protein kinase binding
protein homodimerization activity
protein heterodimerization activity

Annotation information from UniProt.

Sequence

MFRQEQPLAEGSFAPMGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGGQQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAAALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSEHAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
25	N-linked (GlcNAc...) asparagine			UniProt
29	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Adrenaline signalling through Alpha-2 adrenergic receptor	Sus scrofa
Adrenaline,noradrenaline inhibits insulin secretion	Sus scrofa
Adrenoceptors	Sus scrofa
G alpha (i) signalling events	Sus scrofa
G alpha (z) signalling events	Sus scrofa
Surfactant metabolism	Sus scrofa