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Solute carrier family 2, facilitated glucose transporter member 4

Summary

UniProt ID: P19357
Gene Symbol: Slc2a4 Glut4
Gene ID: 25139
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: P19357
PubChem: P19357
Re-Glyco: P19357

Annotation

Keyword: Cell membrane Cytoplasm Glycoprotein Palmitate Phosphoprotein Reference proteome Sugar transport Transmembrane helix Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	Reference
learning or memory	IDA	PMID
short-term memory	IMP	PMID
long-term memory	IMP	PMID
amylopectin biosynthetic process	ISO	GO_REF
positive regulation of brain-derived neurotrophic factor receptor signaling pathway	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

amylopectin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

amylopectin biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

amylopectin biosynthetic process

amylopectin metabolic process [inference]

amylopectin biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

amylopectin biosynthetic process

amylopectin metabolic process [inference]

amylopectin biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation [inference]

brown fat cell differentiation

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stress [inference]

cellular response to osmotic stress

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

D-glucose transmembrane transport

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation [inference]

brown fat cell differentiation

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

response to stimulus [inference]

response to stress [inference]

response to hypoxia [inference]

cellular response to hypoxia

response to osmotic stress [inference]

cellular response to osmotic stress

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress

cellular response to hypoxia

response to abiotic stimulus [inference]

response to osmotic stress [inference]

cellular response to osmotic stress

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stress [inference]

cellular response to osmotic stress

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide [inference]

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to alcohol [inference]

response to ethanol

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stress [inference]

cellular response to osmotic stress

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress

localization [inference]

establishment of localization [inference]

transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

D-glucose transmembrane transport

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

organic anion transport [inference]

dehydroascorbic acid transport

vitamin transport [inference]

dehydroascorbic acid transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

D-glucose transmembrane transport

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

import into cell [inference]

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane [inference]

glucose import in response to insulin stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

regulation of brain-derived neurotrophic factor receptor signaling pathway [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

regulation of brain-derived neurotrophic factor receptor signaling pathway [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

regulation of brain-derived neurotrophic factor receptor signaling pathway [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of brain-derived neurotrophic factor receptor signaling pathway

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of synaptic vesicle budding from presynaptic endocytic zone membrane

Displaying entries **1 - 5** of 53 in total

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GO Term	Evidence Code	Reference
cytoplasm	IDA	PMID
endosome	ISO	GO_REF
endosome	IDA	PMID
endosome	IEA	GO_REF
multivesicular body	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

sarcolemma

clathrin-coated pit

organelle membrane [inference]

vesicle membrane

cytoplasmic vesicle membrane

membrane microdomain [inference]

membrane raft

T-tubule

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome [inference]

multivesicular body

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle

trans-Golgi network transport vesicle

secretory vesicle [inference]

secretory granule [inference]

insulin-responsive compartment

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

sarcoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome [inference]

multivesicular body

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle

trans-Golgi network transport vesicle

secretory vesicle [inference]

secretory granule [inference]

insulin-responsive compartment

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

sarcoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome [inference]

multivesicular body

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle

trans-Golgi network transport vesicle

secretory vesicle [inference]

secretory granule [inference]

insulin-responsive compartment

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

presynapse

Displaying **all 5** entries
GO Term	Evidence Code	Reference
D-glucose uniporter activity	IDA	PMID
D-glucose transmembrane transporter activity	ISO	GO_REF
D-glucose transmembrane transporter activity	IDA	PMID PMID PMID PMID
D-glucose transmembrane transporter activity	IBA	GO_REF
D-glucose transmembrane transporter activity	IEA	GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

carbohydrate transmembrane transporter activity [inference]

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

hexose transmembrane transporter activity [inference]

hexose uniporter activity [inference]

D-glucose uniporter activity

D-glucose transmembrane transporter activity

D-glucose uniporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

uniporter activity [inference]

hexose uniporter activity [inference]

D-glucose uniporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNATWLGRQGPGGPDSIPQGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLANNVLAVLGGALMGLANAAASYEILILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILVAQVLGLESMLGTATLWPLLLAITVLPALLQLLLLPFCPESPRYLYIIRNLEGPARKSLKRLTGWADVSDALAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFELAGVEQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPSMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTCNFIVGMGFQYVADAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISATFRRTPSLLEQEVKPSTELEYLGPDEND

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
57	N-linked (GlcNAc...) asparagine	8573180		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Cellular hexose transport	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements