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MIRAGE
Glutamate receptor 1
Summary
- UniProt ID
- P19490
- Gene Symbol
-
- GluA1
- Glur1
- Gria1
- Gene ID
- 50592
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Ligand-gated ion channel
- Palmitate
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| membrane |
| dendrite |
| neuromuscular junction |
| protein-containing complex |
| somatodendritic compartment |
| neuron projection |
| neuronal cell body |
| cell body |
| synapse |
| postsynaptic membrane |
Sequence
MPYIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIPCMSHSSGMPLGATGL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 63 | N-linked (GlcNAc...) asparagine |
|
||
| 249 | N-linked (GlcNAc...) asparagine |
|
||
| 257 | N-linked (GlcNAc...) asparagine |
|
||
| 363 | N-linked (GlcNAc...) asparagine |
|
||
| 401 | N-linked (GlcNAc...) asparagine |
|
||
| 406 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of AMPA receptors | Rattus norvegicus |
| COPII-mediated vesicle transport | Rattus norvegicus |
| Cargo concentration in the ER | Rattus norvegicus |
| Synaptic adhesion-like molecules | Rattus norvegicus |
| Trafficking of AMPA receptors | Rattus norvegicus |
| Trafficking of GluR2-containing AMPA receptors | Rattus norvegicus |
| Unblocking of NMDA receptors, glutamate binding and activation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060001 | withdrawal disorder | |
| DOID:2560 | morphine dependence | |
| DOID:9279 | hyperhomocysteinemia | |
| DOID:9975 | cocaine dependence |
