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MIRAGE
Tissue-type plasminogen activator
Summary
- UniProt ID
- P19637
- Gene Symbol
- Plat
- Gene ID
- 25692
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Cleavage on pair of basic residues Disulfide bond EGF-like domain Glycoprotein Kringle Plasminogen activation Reference proteome Repeat Secreted Serine protease Signal Zymogen
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| response to hypoxia | ||
| proteolysis | ||
| proteolysis | ||
| smooth muscle cell migration | ||
| smooth muscle cell migration |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| obsolete extracellular space |
|
|
| cytoplasm | ||
| cell surface | ||
| secretory granule | ||
| secretory granule |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| signaling receptor binding | ||
| phosphoprotein binding |
GO Hierarchy
Sequence
MKGELLCVLLLCGVAFTLPDQGIHRRFRRGARSYRATCRDEQTQTTYQQHQSWLRPMLRGNRVEYCRCNSGLAQCHSVPVRSCSEPRCFNGGTCQQALYFSDFVCQCPDGFVGKRCDIDTRATCFEGQGITYRGTWSTAENGAECINWNSSALSQKPYSARRPNAIKLGLGNHNYCRNPDRDVKPWCYVFKAGKYTTEFCSTPACPKGPTEDCYVGKGVTYRGTHSFTTSKASCLPWNSMILIGKTYTAWRANSQALGLGRHNYCRNPDGDAKPWCHVMKDRKLTWEYCDMSPCSTCGLRQYKQPQFRIKGGLFTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCFVERFPPHHLKVVLGRTYRVVPGEEEQTFEIEKYIVHKEFDDDTYDNDIALLQLRSDSSQCAQESSSVGTACLPDPDVQLPDWTECELSGYGKHEASSPFFSDRLKEAHVRLYPSSRCTSQHLFNKTITSNMLCAGDTRTGGNQDVHDACQGDSGGPLVCMIDKRMTLLGIISWGLGCGQKDVPGIYTKVTNYLNWIQDNMKQ
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Dissolution of Fibrin Clot | Rattus norvegicus |
| Signaling by PDGF | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1824 | status epilepticus | |
| DOID:11247 | disseminated intravascular coagulation |
