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MIRAGE
Platelet-derived growth factor subunit A
Summary
- UniProt ID
- P20033
- Gene Symbol
- Pdgfa
- Gene ID
- 18590
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Alternative splicing Cleavage on pair of basic residues Developmental protein Disulfide bond Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| angiogenesis | ||
| angiogenesis | ||
| hair follicle development | ||
| positive regulation of mesenchymal cell proliferation | ||
| positive regulation of cell population proliferation |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| obsolete extracellular space |
|
|
| microvillus | ||
| cell surface | ||
| cell surface | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| platelet-derived growth factor receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| collagen binding |
GO Hierarchy
Sequence
MRTWACLLLLGCGYLAHALAEEAEIPRELIERLARSQIHSIRDLQRLLEIDSVGAEDALETSLRAHGSHAINHVPEKRPVPIRRKRSIEEAIPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATSNLNPDHREEETGRRRESGKKRKRKRLKPT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 134 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signal transduction | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| Platelet degranulation | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
| Signaling by PDGF | Mus musculus |
