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Mimecan

Summary

UniProt ID

P20774

Gene Symbol

OGN
OIF
SLRR3A

Gene ID

[4969]

Organism

Homo sapiens (human)

External Links

GlyConnect

Mimecan

GlyGen

P20774

Re-Glyco

P20774

Annotation

Keyword: Direct protein sequencing Disulfide bond Extracellular matrix Growth factor Leucine-rich repeat Proteoglycan Proteomics identification Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
negative regulation of smooth muscle cell proliferation	ISS	GO_REF
bone development	IBA	GO_REF
articular cartilage development	IBA	GO_REF

GO Hierarchy

biological process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

cartilage development [inference]

articular cartilage development

bone development

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of smooth muscle cell proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of smooth muscle cell proliferation

regulation of smooth muscle cell proliferation [inference]

negative regulation of smooth muscle cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of smooth muscle cell proliferation

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
extracellular region	TAS	Reactome Reactome
extracellular region	HDA	PMID PMID
obsolete extracellular space
Golgi lumen	TAS	Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome
extracellular matrix	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Golgi lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

Displaying 1 entry
GO Term	Evidence Code	Reference
growth factor activity

GO Hierarchy

molecular function

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
80	O-linked (GalNAc...) threonine	19838169 23234360	G29931IJ G43417UB	UniProt GlyGen GlyConnect
88	N-linked (GlcNAc...) (keratan sulfate) asparagine			UniProt GlyGen
214	N-linked (GlcNAc...) (keratan sulfate) asparagine	29741879 37074911	G95046LV G05962QB G12341GU G15169WU G35541EV G80075MS G11629QQ G57776ZS G86880BF G27947YN G52527GH G04854VP G94470IW G87123QX G79666IR G81263BG G45395BF G20706XG G10819WX G40926MX G59536GA G08918WF G00912UN G48414YA G49906RN G70441OD G83646BJ G80223IX G04657PL G27058EU G84452RH G60033FS G41071NU G91636VS G46902YN G72747WU G70619PT G06356OH G59626AS G65184UU G23863VK G90659AW G72790NZ G10486CT	UniProt GlyGen GlyConnect
258	N-linked (GlcNAc...) (keratan sulfate) asparagine	19159218 24190977 37074911	G32788FZ G05962QB G93718GY G57776ZS G68490OW G90382BL G80479JV G79666IR G34989PA G45395BF G07246CJ G43223CG G27915IV G70441OD G76295SF G27058EU G41071NU G08290VR G42124LM G90659AW G47644PP G95177YH G05049YU G18647XP G11314AS	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	Homo sapiens
Defective CHST6 causes MCDC1	Homo sapiens
Defective ST3GAL3 causes MCT12 and EIEE15	Homo sapiens
Keratan sulfate biosynthesis	Homo sapiens
Keratan sulfate degradation	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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International Collaboration

Acknowledgements