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Acetylcholine receptor subunit epsilon
Summary
- UniProt ID
- P20782
- Gene Symbol
-
- Acre
- Chrne
- Gene ID
- [11448]
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Cell membrane Disulfide bond Glycoprotein Ligand-gated ion channel Postsynaptic cell membrane Receptor Reference proteome Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| skeletal muscle contraction | ||
| skeletal muscle contraction | ||
| monoatomic cation transport | ||
| chemical synaptic transmission |
|
|
| synaptic transmission, cholinergic |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| acetylcholine-gated channel complex | ||
| acetylcholine-gated channel complex | ||
| acetylcholine-gated channel complex |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| excitatory extracellular ligand-gated monoatomic ion channel activity |
|
|
| acetylcholine receptor activity | ||
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity |
GO Hierarchy
Sequence
MAGALLGALLLLTLFGRSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIDWHDYRLNYSKDDFAGVGILRVPSEHVWLPEIVLENNIDGQFGVAYDSNVLVYEGGYVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFIFAVDDDGNTINKIDIDTAAFTENGEWAIDYCPGMIRRYEGGSTEGPGETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHATSPRLRQILLELLPRLLGSSPPPEDPRTASPARRASSVGILLRAEELILKKPRSELVFEGQRHRHGTWTAALCQNLGAAAPEIRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYPPCIQP
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110679 | congenital myasthenic syndrome 4C | |
| DOID:0110678 | congenital myasthenic syndrome 4A |
