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MIRAGE
ATP-dependent translocase ABCB1
Summary
- UniProt ID
- P21447
- Gene Symbol
- Abcb1a Abcb4 Mdr1a Mdr3 Pgy-3 Pgy3
- Gene ID
- 18671
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- 3D-structure ATP-binding Cell membrane Cytoplasm Direct protein sequencing Glycoprotein Phosphoprotein Reference proteome Repeat Translocase Transmembrane helix Transport
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| cellular response to antibiotic |
|
|
| cellular response to alkaloid |
|
|
| cellular response to tumor necrosis factor |
|
|
| cellular response to estradiol stimulus |
|
|
| cellular hyperosmotic salinity response |
|
|
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
localization [inference]
biological regulation [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| ATP binding | ||
| ATP binding | ||
| ABC-type xenobiotic transporter activity | ||
| ABC-type xenobiotic transporter activity | ||
| ABC-type xenobiotic transporter activity |
GO Hierarchy
Sequence
MELEEDLKGRADKNFSKMGKKSKKEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIELGNEACKSKDEIDNLDMSSKDSGSSLIRRRSTRKSICGPHDQDRKLSTKEALDEDVPPASFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQAGAKRS
Glycosylation Sites
G40574BA
G61263MF
G36921VW
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABC-family protein mediated transport | Mus musculus |
| Atorvastatin ADME | Mus musculus |
| Prednisone ADME | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110893 | inflammatory bowel disease 13 |
