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Synaptotagmin-1

Summary

UniProt ID

P21707

Gene Symbol

Syt1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P21707
PubChem: P21707

Annotation

Keyword

3D-structure
Calcium
Cytoplasm
Cytoplasmic vesicle
Differentiation
Direct protein sequencing
Glycoprotein
Metal-binding
Palmitate
Phosphoprotein
Reference proteome
Repeat
Synapse
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 26 in total

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GO Term
neurotransmitter secretion
cell differentiation
positive regulation of synaptic transmission
regulation of dopamine secretion
synaptic vesicle exocytosis
positive regulation of vesicle fusion
positive regulation of dopamine secretion
response to calcium ion
regulation of synaptic transmission, glutamatergic
cellular response to calcium ion

Displaying entries **11 - 17** of 17 in total

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GO Term
synaptic vesicle
chromaffin granule membrane
presynaptic membrane
hippocampal mossy fiber to CA3 synapse
cytoplasm
Golgi apparatus
plasma membrane

Displaying entries **1 - 10** of 16 in total

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GO Term
calcium-dependent protein binding
low-density lipoprotein particle receptor binding
calcium ion sensor activity
syntaxin-1 binding
syntaxin binding
clathrin binding
syntaxin-3 binding
identical protein binding
protein heterodimerization activity
SNARE binding

Annotation information from UniProt.

Sequence

MVSASHPEALAAPVTTVATLVPHNATEPASPGEGKEDAFSKLKQKFMNELHKIPLPPWALIAIAIVAVLLVVTCCFCVCKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
24				UniProt GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Acetylcholine Neurotransmitter Release Cycle	Rattus norvegicus
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus
Dopamine Neurotransmitter Release Cycle	Rattus norvegicus
GABA synthesis, release, reuptake and degradation	Rattus norvegicus
Glutamate Neurotransmitter Release Cycle	Rattus norvegicus
Norepinephrine Neurotransmitter Release Cycle	Rattus norvegicus
Serotonin Neurotransmitter Release Cycle	Rattus norvegicus