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Mitogen-activated protein kinase 3

Summary

UniProt ID

P21708

Gene Symbol

Mapk3
Erk1
Prkm3

Organism

Rattus norvegicus (Norway rat)

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell cycle
Cell junction
Cytoplasm
Direct protein sequencing
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
phosphorylation
cartilage development
cardiac neural crest cell development involved in heart development
protein-containing complex assembly
BMP signaling pathway
lipopolysaccharide-mediated signaling pathway
signal transduction in response to DNA damage
insulin-like growth factor receptor signaling pathway
stress-activated MAPK cascade
interleukin-1-mediated signaling pathway

Displaying entries **11 - 16** of 16 in total

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GO Term
nucleus
nuclear envelope
cytoplasm
Golgi apparatus
cytoskeleton
plasma membrane

Displaying **all 10** entries
GO Term
protein kinase activity
protein serine/threonine kinase activity
MAP kinase activity
ATP binding
scaffold protein binding
protein serine kinase activity
DNA-binding transcription factor binding
identical protein binding
phosphatase binding
phosphotyrosine residue binding

Annotation information from UniProt.

Sequence

MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERLKELIFQETARFQPGAPEAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 41 in total

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Pathway Name	Organism
Activation of the AP-1 family of transcription factors	Rattus norvegicus
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Rattus norvegicus
ERK/MAPK targets	Rattus norvegicus
ERKs are inactivated	Rattus norvegicus
FCERI mediated MAPK activation	Rattus norvegicus
Frs2-mediated activation	Rattus norvegicus
Gastrin-CREB signalling pathway via PKC and MAPK	Rattus norvegicus
Golgi Cisternae Pericentriolar Stack Reorganization	Rattus norvegicus
Growth hormone receptor signaling	Rattus norvegicus
IFNG signaling activates MAPKs	Rattus norvegicus