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MIRAGE
Fibroblast growth factor receptor 2
Summary
- UniProt ID
- P21803
- Gene Symbol
- Fgfr2 Bek Ect1
- Gene ID
- 14183
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003479
- GlyGen
- P21803
- PubChem
- P21803
- Re-Glyco
- P21803
Annotation
- Keyword
- 3D-structure ATP-binding Alternative splicing Apoptosis Cell membrane Cytoplasmic vesicle Disulfide bond Glycoprotein Golgi apparatus Heparin-binding Immunoglobulin domain Phosphoprotein Proto-oncogene Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| angiogenesis | ||
| angiogenesis | ||
| ureteric bud development | ||
| in utero embryonic development |
GO Hierarchy
- fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell
- fibroblast growth factor receptor signaling pathway involved in hemopoiesis
- fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
- fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
- fibroblast growth factor receptor apoptotic signaling pathway
- synaptic vesicle transport
- membranous septum morphogenesis
- hair follicle morphogenesis
- lung lobe morphogenesis
- fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell
- fibroblast growth factor receptor signaling pathway involved in hemopoiesis
- fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
- fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
- fibroblast growth factor receptor apoptotic signaling pathway
biological process
cellular process [inference]
signal transduction [inference]
cell surface receptor signaling pathway [inference]
enzyme-linked receptor protein signaling pathway [inference]
cell surface receptor protein tyrosine kinase signaling pathway [inference]
fibroblast growth factor receptor signaling pathway
reproductive process [inference]
multicellular organismal process [inference]
developmental process [inference]
developmental process involved in reproduction [inference]
anatomical structure morphogenesis [inference]
morphogenesis of a branching structure [inference]
tissue morphogenesis [inference]
anatomical structure development [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
cell surface receptor signaling pathway [inference]
enzyme-linked receptor protein signaling pathway [inference]
cell surface receptor protein tyrosine kinase signaling pathway [inference]
fibroblast growth factor receptor signaling pathway
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell population proliferation
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| fibroblast growth factor receptor activity | ||
| fibroblast growth factor receptor activity | ||
| fibroblast growth factor receptor activity | ||
| ATP binding | ||
| heparin binding |
|
|
GO Hierarchy
Sequence
MVSWGRFICLVLVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEAYVVAPGESLELQCMLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTAARTVDSETWIFMVNVTDAISSGDDEDDTDSSEDVVSENRSNQRAPYWTNTEKMEKRLHACPAANTVKFRCPAGGNPTSTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKNGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLEQYSPSYPDTSSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 83 |
|
|||
| 123 |
|
|
||
| 147 |
|
|
||
| 228 |
|
|
||
| 241 |
|
|
||
| 265 |
|
|||
| 297 |
|
|
||
| 318 |
|
|||
| 331 |
|
|
G07755XJ
G80920RR
G60834IK
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Mus musculus |
| FGFR2c ligand binding and activation | Mus musculus |
| FRS-mediated FGFR2 signaling | Mus musculus |
| Negative regulation of FGFR2 signaling | Mus musculus |
| PI-3K cascade:FGFR2 | Mus musculus |
| PI3K Cascade | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| Phospholipase C-mediated cascade; FGFR2 | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
