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MIRAGE
Coagulation factor VII
Summary
- UniProt ID
- P22457
- Gene Symbol
-
- F7
- Gene ID
- [617960]
- Organism
- Bos taurus (domestic cattle)
Annotation
- Keyword
- Blood coagulation Calcium Cleavage on pair of basic residues Direct protein sequencing Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Reference proteome Repeat Secreted Serine protease Signal Zymogen
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| blood coagulation | ||
| blood coagulation | ||
| protein processing |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| obsolete extracellular space |
|
|
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| calcium ion binding |
GO Hierarchy
Sequence
MLSQAWALALLCFLLSLWGSLPAVFLPQEQALSILHRPRRANGFLEELLPGSLERECREELCSFEEAHEIFRNEERTRQFWVSYNDGDQCASSPCQNGGSCEDQLRSYICFCPDGFEGRNCETDKQSQLICANDNGGCEQYCGADPGAGRFCWCHEGYALQADGVSCAPTVEYPCGKIPVLEKRNGSKPQGRIVGGHVCPKGECPWQAMLKLNGALLCGGTLVGPAWVVSAAHCFERLRSRGNLTAVLGEHDLSRVEGPEQERRVAQIIVPKQYVPGQTDHDVALLQLAQPVALGDHVAPLCLPDPDFADQTLAFVRFSAVSGWGQLLERGVTARKLMVVLVPRLLTQDCLQQSRQRPGGPVVTDNMFCAGYSDGSKDACKGDSGGPHATRFRGTWFLTGVVSWGEGCAAAGHFGIYTRVSRYTAWLRQLMGHPPSRQGFFQVPLLP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 92 |
|
|
||
| 100 |
|
|
||
| 185 |
|
|
||
| 243 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Gamma-carboxylation of protein precursors | Bos taurus |
| Initiation of coagulation cascade | Bos taurus |
| Regulation of clotting cascade | Bos taurus |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Bos taurus |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | Bos taurus |
