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MIRAGE
Tumor necrosis factor receptor superfamily member 1A
Summary
- UniProt ID
- P22934
- Gene Symbol
-
- Tnfr-1
- Tnfr1
- Tnfrsf1a
- Gene ID
- 25625
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Apoptosis
- Cell membrane
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| axon |
| protein-containing complex |
| receptor complex |
| Golgi membrane |
| cell surface |
| membrane raft |
| GO Term |
|---|
| protease binding |
| protein-containing complex binding |
| signaling receptor activity |
| tumor necrosis factor receptor activity |
| tumor necrosis factor binding |
Sequence
MGLPIVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDNLCPQGKYAHPKNNSICCTKCHKGTYLVSDCPSPGQETVCEVCDKGTFTASQNHVRQCLSCKTCRKEMFQVEISPCKADMDTVCGCKKNQFQRYLSETHFQCVDCSPCFNGTVTIPCKEKQNTVCNCHAGFFLSGNECTPCSHCKKNQECMKLCLPPVANVTNPQDSGTAVLLPLVIFLGLCLLFFICISLLCRYPQWRPRVYSIICRDSAPVKEVEGEGIVTKPLTPASIPAFSPNPGFNPTLGFSTTPRFSHPVSSTPISPVFGPSNWHNFVPPVREVVPTQGADPLLYGSLNPVPIPAPVRKWEDVVAAQPQRLDTADPAMLYAVVDGVPPTRWKEFMRLLGLSEHEIERLELQNGRCLREAHYSMLEAWRRRTPRHEATLDVVGRVLCDMNLRGCLENIRETLESPAHSSTTHLPR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of TNFR1 signaling | Rattus norvegicus |
| TNF signaling | Rattus norvegicus |
| TNFR1-induced NF-kappa-B signaling pathway | Rattus norvegicus |
| TNFR1-induced proapoptotic signaling | Rattus norvegicus |
| TNFR1-mediated ceramide production | Rattus norvegicus |
| TNFs bind their physiological receptors | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11832 | visual epilepsy | |
| DOID:13141 | uveitis | |
| DOID:2316 | brain ischemia | |
| DOID:326 | ischemia | |
| DOID:3525 | middle cerebral artery infarction | |
| DOID:5844 | myocardial infarction |
