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MIRAGE

Peptidyl-prolyl cis-trans isomerase B

Summary

UniProt ID: P24369
Gene Symbol: Ppib CyP-20b
Gene ID: 19035
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003507
GlyGen: P24369
PubChem: P24369
RaftProt: P24369
Re-Glyco: P24369

Annotation

Keyword: Acetylation Endoplasmic reticulum Reference proteome Rotamase Signal

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
protein folding	ISS	GO_REF
protein folding	ISO	GO_REF
protein folding	IBA	GO_REF
protein folding	IEA	GO_REF GO_REF
neutrophil chemotaxis	ISO	GO_REF

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cellular process [inference]

protein folding

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

developmental process [inference]

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

animal organ development [inference]

bone development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

host-mediated perturbation of symbiont process [inference]

host-mediated perturbation of viral process [inference]

host-mediated activation of viral process

host-mediated activation of viral genome replication

host-mediated perturbation of viral genome replication [inference]

host-mediated activation of viral genome replication

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of developmental growth [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of multicellular organismal process [inference]

regulation of multicellular organism growth [inference]

positive regulation of multicellular organism growth

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

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GO Term	Evidence Code	Reference
nucleoplasm	ISO	GO_REF
cytoplasm
endoplasmic reticulum	ISO	GO_REF
endoplasmic reticulum	IEA	GO_REF
endoplasmic reticulum lumen	ISS	GO_REF

GO Hierarchy

cellular component

protein-containing complex

endoplasmic reticulum protein-containing complex [inference]

endoplasmic reticulum chaperone complex

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

smooth endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

smooth endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

perinuclear region of cytoplasm

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GO Term	Evidence Code	Reference
peptidyl-prolyl cis-trans isomerase activity	ISS	GO_REF
peptidyl-prolyl cis-trans isomerase activity	ISO	GO_REF
peptidyl-prolyl cis-trans isomerase activity	IEA	GO_REF GO_REF GO_REF GO_REF
cyclosporin A binding	IBA	GO_REF
RNA polymerase binding	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

isomerase activity [inference]

cis-trans isomerase activity [inference]

peptidyl-prolyl cis-trans isomerase activity

catalytic activity, acting on a protein [inference]

peptidyl-prolyl cis-trans isomerase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

RNA polymerase binding

cyclosporin A binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPFAIAKE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
148			G80920RR	GlycoProtDB GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Collagen biosynthesis and modifying enzymes	Mus musculus

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026