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Adenosine receptor A1

Summary

UniProt ID

P25099

Gene Symbol

Adora1

Gene ID

29290

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P25099
Re-Glyco: P25099

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 14 in total

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GO Term
basolateral plasma membrane
axolemma
asymmetric synapse
presynaptic membrane
terminal bouton
dendritic spine
calyx of Held
presynaptic active zone
plasma membrane
dendrite

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 48 in total

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GO Term
regulation of sensory perception of pain
negative regulation of synaptic transmission, glutamatergic
regulation of cardiac muscle contraction
excitatory postsynaptic potential
negative regulation of mucus secretion
temperature homeostasis
response to hypoxia
regulation of respiratory gaseous exchange by nervous system process
negative regulation of acute inflammatory response
negative regulation of leukocyte migration

Displaying **all 8** entries
GO Term
heat shock protein binding
purine nucleoside binding
heterotrimeric G-protein binding
protein-containing complex binding
protein heterodimerization activity
G-protein beta/gamma-subunit complex binding
G protein-coupled adenosine receptor activity
G protein-coupled receptor binding

Annotation information from UniProt.

Sequence

MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
148	N-linked (GlcNAc...) asparagine			UniProt
159	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Adenosine P1 receptors	Rattus norvegicus
G alpha (i) signalling events	Rattus norvegicus

Disease

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050848	obstructive sleep apnea	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:3526	cerebral infarction	Alliance of Genome Resources
DOID:850	lung disease	Alliance of Genome Resources