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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
Tumor necrosis factor receptor superfamily member 6
Summary
- UniProt ID
- P25446
- Gene Symbol
-
- Apt1
- Fas
- Tnfrsf6
- Gene ID
- 14102
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Apoptosis
- Calmodulin-binding
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| CD95 death-inducing signaling complex |
| membrane raft |
| extracellular region |
| cell surface |
| external side of plasma membrane |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| calmodulin binding |
| identical protein binding |
Sequence
MLWIWAVLPLVLAGSQLRVHTQGTNSISESLKLRRRVRETDKNCSEGLYQGGPFCCQPCQPGKKKVEDCKMNGGTPTCAPCTEGKEYMDKNHYADKCRRCTLCDEEHGLEVETNCTLTQNTKCKCKPDFYCDSPGCEHCVRCASCEHGTLEPCTATSNTNCRKQSPRNRLWLLTILVLLIPLVFIYRKYRKRKCWKRRQDDPESRTSSRETIPMNASNLSLSKYIPRIAEDMTIQEAKKFARENNIKEGKIDEIMHDSIQDTAEQKVQLLLCWYQSHGKSDAYQDLIKGLKKAECRRTLDKFQDMVQKDLGKSTPDTGNENEGQCLE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 43 | N-linked (GlcNAc...) asparagine |
|
||
| 114 | N-linked (GlcNAc...) asparagine | |||
| 144 |
|
|||
| 154 |
|
|||
| 215 |
|
G45504EY
G49108TO
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Mus musculus |
| Dimerization of procaspase-8 | Mus musculus |
| FasL/ CD95L signaling | Mus musculus |
| Regulation by c-FLIP | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12894 | Sjogren's syndrome | |
| DOID:6688 | autoimmune lymphoproliferative syndrome | |
| DOID:9074 | systemic lupus erythematosus |
