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Heparin sulfate O-sulfotransferase

Summary

UniProt ID: P25722
Gene Symbol: CG10234 HS-2OST Hs2st
Gene ID: 44433
Organism: Drosophila melanogaster (fruit fly)

External Links

PubChem: P25722
Re-Glyco: P25722

Annotation

Keyword: Alternative splicing Disulfide bond Glycoprotein Golgi apparatus Reference proteome Signal-anchor Transferase Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
signal transduction	NAS	PMID
open tracheal system development	IMP	PMID
open tracheal system development	IGI	PMID
heparan sulfate proteoglycan biosynthetic process	IMP	PMID PMID PMID
heparan sulfate proteoglycan biosynthetic process	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

heparan sulfate proteoglycan biosynthetic process

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

heparan sulfate proteoglycan biosynthetic process

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

heparan sulfate proteoglycan biosynthetic process

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

heparan sulfate proteoglycan biosynthetic process

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

heparan sulfate proteoglycan biosynthetic process

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

heparan sulfate proteoglycan biosynthetic process

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

heparan sulfate proteoglycan biosynthetic process

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

respiratory system development [inference]

open tracheal system development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying **all 3** entries
GO Term	Evidence Code	Reference
Golgi membrane	ISS	GO_REF
Golgi membrane	IEA	GO_REF
Golgi apparatus	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	Reference
heparan sulfate 2-sulfotransferase activity	IDA	PMID PMID
heparan sulfate 2-sulfotransferase activity	IBA	GO_REF
heparan sulfate 2-sulfotransferase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity [inference]

proteoglycan sulfotransferase activity [inference]

heparan sulfate sulfotransferase activity [inference]

heparan sulfate 2-sulfotransferase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MFRKLLKMWILLRPTHWLILIALCAVTCAGYWLLWSEIRLEHAFKPLSKLGDSLSPDQHASSTTDDFDFEEHLVVLYNRVPKTGSTSFVNIAYDLCKPNKFHVLHINVTANMHVLSLPNQIQFVRNVSRWHEMKPALYHGHMAFLDFSKFQIAHKPIYINLVRKPLDRLVSYYYFLRFGDNYRPNLVRKKAGNKITFDECVVQKQPDCDPKNMWLQIPFFCGHAAECWEPGSSWALDQAKRNLVNEYFLVGVTEQMYEFVDLLERSLPRIFHGFREHYHNSNKSHLRVTSSKLPPSESTIKSIQKTKIWQMENDLYDFALAQFEFNKKKLMQPDNKHVQKFMYEKIRPK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
107	N-linked (GlcNAc...) asparagine	UniProt
126	N-linked (GlcNAc...) asparagine	UniProt
282	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
HS-GAG biosynthesis	Drosophila melanogaster

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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