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Tyrosine-protein kinase Lyn

Summary

UniProt ID: P25911
Gene Symbol: Lyn
Gene ID: 17096
Organism: Mus musculus (house mouse)

External Links

GlyGen: P25911
PubChem: P25911
The Human Metabolome Database: HMDBP13813
The O-GlcNAc Database: P25911
RaftProt: P25911
O-GlcNAcAtlas: P25911
Re-Glyco: P25911

Annotation

Keyword: 3D-structure ATP-binding Adaptive immunity Alternative splicing Cell membrane Cytoplasm Golgi apparatus Inflammatory response Innate immunity Myristate Nucleus Palmitate Phosphoprotein Proto-oncogene Reference proteome SH2 domain SH3 domain Tyrosine-protein kinase Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 96 in total

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GO Term	Evidence Code	Reference
DNA damage checkpoint signaling	ISO	GO_REF
cell morphogenesis	IGI	PMID
B cell homeostasis	IMP	PMID
regulation of cytokine production	IMP	PMID PMID
negative regulation of protein phosphorylation	IMP	PMID

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

tolerance induction [inference]

tolerance induction to self antigen

immune response [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation [inference]

B cell proliferation

lymphocyte proliferation [inference]

B cell proliferation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation [inference]

B cell proliferation

lymphocyte proliferation [inference]

B cell proliferation

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

ephrin receptor signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-5-mediated signaling pathway

chemokine-mediated signaling pathway [inference]

C-X-C chemokine receptor CXCR4 signaling pathway

lipopolysaccharide-mediated signaling pathway

G protein-coupled receptor signaling pathway [inference]

chemokine-mediated signaling pathway [inference]

C-X-C chemokine receptor CXCR4 signaling pathway

intracellular signal transduction

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

catabolic process [inference]

autophagy

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

protein metabolic process [inference]

hemoglobin metabolic process [inference]

hemoglobin biosynthetic process

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process [inference]

hemoglobin biosynthetic process

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

granulocyte differentiation [inference]

eosinophil differentiation

mononuclear cell differentiation [inference]

dendritic cell differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

granulocyte differentiation [inference]

eosinophil differentiation

erythrocyte differentiation

cell development [inference]

glial cell development [inference]

oligodendrocyte development

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

process utilizing autophagic mechanism [inference]

autophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

exocytic process [inference]

histamine secretion by mast cell

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

signal release [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

B cell activation [inference]

B cell proliferation

lymphocyte proliferation [inference]

B cell proliferation

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure development [inference]

cell development [inference]

glial cell development [inference]

oligodendrocyte development

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

granulocyte differentiation [inference]

eosinophil differentiation

mononuclear cell differentiation [inference]

dendritic cell differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

granulocyte differentiation [inference]

eosinophil differentiation

erythrocyte differentiation

cell development [inference]

glial cell development [inference]

oligodendrocyte development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

neuroinflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to sterol depletion

response to heat [inference]

cellular response to heat

response to wounding [inference]

response to axon injury

cellular response to stress [inference]

cellular response to DNA damage stimulus

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to heat

immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

response to endogenous stimulus [inference]

response to hormone

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to acid chemical [inference]

response to amino acid

response to hormone

response to peptide hormone [inference]

response to insulin

response to lipid [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to carbohydrate

response to retinoic acid [inference]

cellular response to retinoic acid

response to peptide hormone [inference]

response to insulin

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to retinoic acid

cellular response to oxygen-containing compound [inference]

cellular response to retinoic acid

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

fatty acid transport

hormone transport [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

secretion [inference]

histamine secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

signal release [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

nitrogen compound transport [inference]

histamine transport [inference]

histamine secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

platelet degranulation

signal release [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

establishment of localization in cell [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of leukocyte migration [inference]

regulation of leukocyte chemotaxis [inference]

regulation of monocyte chemotaxis

regulation of mononuclear cell migration [inference]

regulation of monocyte chemotaxis

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of mast cell activation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of immune effector process [inference]

regulation of leukocyte mediated immunity [inference]

regulation of myeloid leukocyte mediated immunity [inference]

regulation of mast cell degranulation

regulation of leukocyte degranulation [inference]

regulation of mast cell degranulation

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of B cell receptor signaling pathway

negative regulation of B cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of erythrocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of B cell receptor signaling pathway

negative regulation of B cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of ERK1 and ERK2 cascade

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

regulation of mast cell degranulation

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

regulation of mast cell degranulation

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

regulation of monocyte chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of leukocyte chemotaxis [inference]

regulation of monocyte chemotaxis

regulation of mononuclear cell migration [inference]

regulation of monocyte chemotaxis

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of glial cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of oligodendrocyte progenitor proliferation

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of mast cell proliferation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of B cell receptor signaling pathway

negative regulation of B cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of ERK1 and ERK2 cascade

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of inflammatory response

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

regulation of monocyte chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of Fc receptor mediated stimulatory signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of B cell receptor signaling pathway

negative regulation of B cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of erythrocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of erythrocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

immune response-regulating cell surface receptor signaling pathway

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

Fc receptor mediated stimulatory signaling pathway

antigen receptor-mediated signaling pathway [inference]

B cell receptor signaling pathway

immune response-inhibiting cell surface receptor signaling pathway [inference]

Fc receptor mediated inhibitory signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

ephrin receptor signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-5-mediated signaling pathway

chemokine-mediated signaling pathway [inference]

C-X-C chemokine receptor CXCR4 signaling pathway

lipopolysaccharide-mediated signaling pathway

G protein-coupled receptor signaling pathway [inference]

chemokine-mediated signaling pathway [inference]

C-X-C chemokine receptor CXCR4 signaling pathway

intracellular signal transduction

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

regulation of antigen receptor-mediated signaling pathway [inference]

regulation of B cell receptor signaling pathway

negative regulation of B cell receptor signaling pathway

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

regulation of Fc receptor mediated stimulatory signaling pathway [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of ERK1 and ERK2 cascade

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

positive regulation of phosphorylation

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

regulation of homotypic cell-cell adhesion [inference]

regulation of platelet aggregation

regulation of cell adhesion mediated by integrin

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of glial cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of oligodendrocyte progenitor proliferation

negative regulation of cell population proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of mast cell proliferation

regulation of glial cell proliferation [inference]

positive regulation of glial cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of mast cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

regulation of mast cell proliferation [inference]

regulation of neural precursor cell proliferation [inference]

regulation of oligodendrocyte progenitor proliferation [inference]

positive regulation of oligodendrocyte progenitor proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of oligodendrocyte progenitor proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

regulation of leukocyte apoptotic process [inference]

regulation of lymphocyte apoptotic process [inference]

regulation of B cell apoptotic process

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

regulation of dendritic cell apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of erythrocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of glial cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of oligodendrocyte progenitor proliferation

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Fc receptor mediated stimulatory signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of mast cell proliferation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of antigen receptor-mediated signaling pathway [inference]

negative regulation of B cell receptor signaling pathway

negative regulation of intracellular signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of mast cell activation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of platelet activation [inference]

regulation of platelet aggregation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

regulation of mast cell degranulation

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

regulation of mast cell degranulation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of leukocyte chemotaxis [inference]

regulation of monocyte chemotaxis

regulation of mononuclear cell migration [inference]

regulation of monocyte chemotaxis

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of mast cell activation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

regulation of platelet activation [inference]

regulation of platelet aggregation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of B cell proliferation

negative regulation of B cell activation [inference]

negative regulation of B cell proliferation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of erythrocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

histamine secretion involved in inflammatory response [inference]

histamine secretion by mast cell

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity [inference]

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

negative regulation of MAP kinase activity

negative regulation of protein serine/threonine kinase activity [inference]

negative regulation of MAP kinase activity

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	Reference
nucleus	ISO	GO_REF
nucleus	IDA	PMID
nucleus	IEA	GO_REF
cytoplasm	IDA	PMID
cytoplasm	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex [inference]

integrin alpha2-beta1 complex

protein complex involved in cell adhesion [inference]

integrin complex [inference]

integrin alpha2-beta1 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex [inference]

integrin alpha2-beta1 complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

mitochondrial membrane

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

mitochondrial crista

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

postsynaptic specialization, intracellular component

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular membraneless organelle [inference]

postsynaptic specialization, intracellular component

perinuclear region of cytoplasm

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

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GO Term	Evidence Code	Reference
protein kinase activity	IDA	PMID
protein kinase activity	IEA	GO_REF
protein tyrosine kinase activity	ISO	GO_REF GO_REF
protein tyrosine kinase activity	EXP	PMID PMID PMID
protein tyrosine kinase activity	TAS	Reactome

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

binding [inference]

protein binding [inference]

signaling receptor binding

cytokine receptor binding [inference]

erythropoietin receptor binding

growth factor receptor binding [inference]

platelet-derived growth factor receptor binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

gamma-tubulin binding

enzyme binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

protein domain specific binding [inference]

SH3 domain binding

transmembrane transporter binding

cell adhesion molecule binding [inference]

integrin binding

modification-dependent protein binding [inference]

phosphorylation-dependent protein binding

lipid binding [inference]

sphingolipid binding [inference]

glycosphingolipid binding

glycolipid binding [inference]

glycosphingolipid binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

integrin binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

glycolipid binding [inference]

glycosphingolipid binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

kinase regulator activity [inference]

phosphatidylinositol 3-kinase regulator activity [inference]

phosphatidylinositol 3-kinase activator activity

signaling receptor regulator activity [inference]

signaling receptor activator activity

molecular function activator activity [inference]

signaling receptor activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGCIKSKRKDNLNDDEVDSKTQPVRNTDRTIYVRDPTSNKQQRPVPEFHLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
19		29187734 37507081	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
CD209 (DC-SIGN) signaling	Mus musculus
CD22 mediated BCR regulation	Mus musculus
CD28 co-stimulation	Mus musculus
Co-inhibition by CTLA4	Mus musculus
Cyclin D associated events in G1	Mus musculus
Dectin-2 family	Mus musculus
EPH-ephrin mediated repulsion of cells	Mus musculus
EPHA-mediated growth cone collapse	Mus musculus
EPHB-mediated forward signaling	Mus musculus
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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