GlyCosmos Portal

Submissions

Hepatocyte growth factor-like protein

Summary

UniProt ID: P26927
Gene Symbol: MST1 D3F15S2 DNF15S2 HGFL hCG_2001992
Gene ID: 4485
Organism: Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011640

GlyConnect

Hepatocyte growth factor-like protein

GlyGen

P26927

PubChem

P26927

Re-Glyco

P26927

Annotation

Keyword: 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Kringle Proteomics identification Reference proteome Repeat Secreted Serine protease homolog Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
proteolysis	IEA	GO_REF
negative regulation of gluconeogenesis	IDA	PMID
regulation of receptor signaling pathway via JAK-STAT	IBA	GO_REF
regulation of cAMP-dependent protein kinase activity	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of macromolecule metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of transferase activity [inference]

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

Displaying **all 5** entries
GO Term	Evidence Code	Reference
extracellular region	TAS	Reactome Reactome Reactome Reactome
extracellular region	IDA	PMID
extracellular region	IEA	GO_REF
obsolete extracellular space
extracellular matrix	HDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

Displaying **all 3** entries
GO Term	Evidence Code	Reference
receptor tyrosine kinase binding	IDA	PMID
receptor tyrosine kinase binding	IBA	GO_REF
receptor tyrosine kinase binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor tyrosine kinase binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPWQEDVADAEECAGRCGPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPPDQVQFEKCGKRVDRLDQRRSKLRVVGGHPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVTLNQRVALICLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMRLG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
72	N-linked (GlcNAc...) asparagine	29391424 29671580 37074911	G04854VP G94470IW G00912UN G48414YA	GlycoProtDB UniProt GlyGen GlyConnect
155		29391424	G48414YA G06356OH	GlyGen GlyConnect
238		29391424	G57888GL	GlyGen GlyConnect
296	N-linked (GlcNAc...) asparagine	16335952 29391424 29671580 29741879 37074911	G93656SY G08918WF G00912UN G48414YA G83460ZZ G06356OH G59626AS G80920RR G62765YT G31852PQ	GlycoProtDB UniProt GlyGen GlyConnect
407		30459171	G43417UB	GlyGen
615	N-linked (GlcNAc...) asparagine	19159218 29391424 29741879 37074911	G06247RL G45395BF G10846ZT G40574BA G08918WF G00912UN G48414YA G70619PT G59626AS G83633GK G62765YT G31852PQ	GlycoProtDB UniProt GlyGen GlyConnect