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MIRAGE
Activin receptor type-2A
Summary
- UniProt ID
- P27038
- Gene Symbol
- Acvr2 Acvr2a
- Gene ID
- 11480
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003524
- PubChem
- P27038
- Re-Glyco
- P27038
Annotation
- Keyword
- 3D-structure ATP-binding Cell membrane Disulfide bond Glycoprotein Magnesium Manganese Metal-binding Receptor Reference proteome Serine/threonine-protein kinase Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| osteoblast differentiation | ||
| osteoblast differentiation | ||
| gastrulation with mouth forming second | ||
| gastrulation with mouth forming second | ||
| autophagy |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| ATP binding | ||
| coreceptor activity |
GO Hierarchy
Sequence
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 43 |
|
|
||
| 66 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Signaling by Activin | Mus musculus |
| Signaling by BMP | Mus musculus |
| TGFBR3 regulates activin signaling | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4258 | Weissenbacher-Zweymuller syndrome |
