Properdin

Summary
UniProt ID
P27918
Gene Symbol
  • CFP
  • PFC
Gene ID
5199
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011643
GlyGen
P27918
PubChem
P27918
Re-Glyco
P27918
Annotation
Keyword
  • 3D-structure
  • Complement alternate pathway
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
Gene Ontology (GO)
Sequence
MITEGAQAPRLLLPPLLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL
Glycosylation Sites
Displaying entries 1 - 10 of 20 in total
Position Description PubMed ID GlyTouCan ID Source
83 ["C-linked (Man) tryptophan"]
86 ["C-linked (Man) tryptophan"]
92 ["O-linked (Fuc...) threonine"]
139 ["C-linked (Man) tryptophan"]
142 ["C-linked (Man) tryptophan"]
145 ["C-linked (Man) tryptophan"]
151 ["O-linked (Fuc...) threonine"]
196 ["C-linked (Man) tryptophan"]
199 ["C-linked (Man) tryptophan"]
202 ["C-linked (Man) tryptophan"]
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Defective B3GALTL causes PpS Homo sapiens
Neutrophil degranulation Homo sapiens
O-glycosylation of TSR domain-containing proteins Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0111768 X-linked properdin deficiency

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026