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D-beta-hydroxybutyrate dehydrogenase, mitochondrial

Summary

UniProt ID: P29147
Gene Symbol: Bdh Bdh1
Gene ID: 117099
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: P29147
PubChem: P29147
O-GlcNAcAtlas: P29147
Re-Glyco: P29147

Annotation

Keyword: Acetylation Allosteric enzyme Direct protein sequencing Glycoprotein Lipid metabolism Mitochondrion inner membrane NAD Oxidoreductase Phosphoprotein Reference proteome Transit peptide

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
liver development	IEP	PMID
response to nutrient	IEP	PMID
steroid metabolic process
response to xenobiotic stimulus	IEP	PMID
response to toxic substance	IEP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

connective tissue development [inference]

adipose tissue development

animal organ development [inference]

gland development [inference]

liver development

response to stimulus [inference]

response to stress [inference]

response to starvation

response to endogenous stimulus [inference]

response to hormone

response to peptide hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to nutrient levels [inference]

response to chemical [inference]

response to hormone

response to peptide hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to metal ion [inference]

response to cadmium ion

response to lipid [inference]

response to estradiol

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to oxygen-containing compound [inference]

response to estradiol

response to peptide hormone [inference]

response to alcohol [inference]

response to ketone [inference]

response to corticosterone

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GO Term	Evidence Code	Reference
mitochondrion
mitochondrial inner membrane	IDA	PMID
mitochondrial inner membrane	IBA	GO_REF
mitochondrial inner membrane	IEA	GO_REF
mitochondrial matrix	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

side of membrane [inference]

lumenal side of membrane [inference]

matrix side of mitochondrial inner membrane

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GO Term	Evidence Code	Reference
3-hydroxybutyrate dehydrogenase activity	ISO	GO_REF
3-hydroxybutyrate dehydrogenase activity	TAS	PMID
3-hydroxybutyrate dehydrogenase activity	IDA	PMID
3-hydroxybutyrate dehydrogenase activity	IBA	GO_REF
3-hydroxybutyrate dehydrogenase activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-hydroxybutyrate dehydrogenase activity

binding [inference]

lipid binding [inference]

phospholipid binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLAARLSRPLSQLPGKALSVCDRENGTRHTLLFYPASFSPDTRRTYTSQADAASGKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLLKDKGDAGVRELDSLKSDRLRTIQLNVCNSEEVEKAVETVRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDELPEVVRKDYGKKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQVMTHFPGAISDKIYIH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites