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MIRAGE
Polyadenylate-binding protein 1
Summary
- UniProt ID
- P29341
- Gene Symbol
- Pabpc1 Pabp1
- Gene ID
- 18458
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Acetylation Cell projection Cytoplasm Methylation Nonsense-mediated mRNA decay Nucleus Phosphoprotein RNA-binding Reference proteome Repeat Spliceosome
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
|
|
| mRNA processing |
|
|
| RNA splicing |
|
|
| gene silencing by RNA | ||
| regulatory ncRNA-mediated gene silencing |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| RNA binding | ||
| RNA binding | ||
| mRNA binding | ||
| mRNA binding | ||
| mRNA 3'-UTR binding |
Sequence
MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPSLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 485 |
|
|||
| 502 |
|
|
||
| 531 |
|
|||
| 546 |
|
|||
| 548 |
|
|||
| 629 |
|
|||
| 631 |
|
|||
| 635 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AUF1 (hnRNP D0) binds and destabilizes mRNA | Mus musculus |
| Deadenylation of mRNA | Mus musculus |
| L13a-mediated translational silencing of Ceruloplasmin expression | Mus musculus |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | Mus musculus |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | Mus musculus |
| Translation initiation complex formation | Mus musculus |
