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MIRAGE
Platelet-derived growth factor subunit B
Summary
- UniProt ID
- P31240
- Gene Symbol
- Pdgfb Sis
- Gene ID
- 18591
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Cleavage on pair of basic residues Developmental protein Disulfide bond Glycoprotein Growth factor Mitogen Proto-oncogene Reference proteome Secreted Signal
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| angiogenesis | ||
| blood vessel development | ||
| embryonic placenta development | ||
| positive regulation of endothelial cell proliferation | ||
| positive regulation of endothelial cell proliferation |
GO Hierarchy
- positive regulation of cell division
- positive regulation of vascular associated smooth muscle cell dedifferentiation
- positive regulation of cell division
- positive regulation of vascular associated smooth muscle cell dedifferentiation
biological process
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of metabolic process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| obsolete extracellular space |
|
|
| cytoplasm | ||
| cytoplasm | ||
| cell surface | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| signaling receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| platelet-derived growth factor receptor binding | ||
| collagen binding |
GO Hierarchy
Sequence
MNRCWALFLPLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHRDSVDEDGAELDLNMTRAHSGVELESSSRGRRSLGSLAAAEPAVIAECKTRTEVFQISRNLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRASQVQMRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETIVTPRPVTRSPGTSREQRAKTPQARVTIRTVRIRRPPKGKHRKFKHTHDKAALKETLGA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 63 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signal transduction | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| Platelet degranulation | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
| Signaling by PDGF | Mus musculus |
