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Amphiregulin

Summary

UniProt ID

P31955

Gene Symbol

Areg
Sdgf

Organism

Mus musculus (house mouse)

External Links

PubChem: P31955

Annotation

Keyword

Cytokine
Disulfide bond
EGF-like domain
Glycoprotein
Growth factor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 18 in total

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GO Term
G protein-coupled receptor signaling pathway
positive regulation of cell population proliferation
positive regulation of phosphorylation
glial cell proliferation
neuron projection development
response to estradiol
response to peptide hormone
negative regulation of osteoblast differentiation
positive regulation of peptidyl-tyrosine phosphorylation
response to glucocorticoid

Displaying **all 5** entries
GO Term
cell surface
extracellular space
nucleus
cytoplasm
membrane

Displaying **all 5** entries
GO Term
growth factor activity
transmembrane receptor protein tyrosine kinase activator activity
cytokine activity
receptor ligand activity
epidermal growth factor receptor binding

Annotation information from UniProt.

Sequence

MRTPLLPLARSVLLLLVLGSGHYAAALELNDPSSGKGESLSGDHSAGGLELSVGREVSTISEMPSGSELSTGDYDYSEEYDNEPQISGYIIDDSVRVEQVIKPKKNKTEGEKSTEKPKRKKKGGKNGKGRRNKKKKNPCTAKFQNFCIHGECRYIENLEVVTCNCHQDYFGERCGEKSMKTHSEDDKDLSKIAVVAVTIFVSAIILAAIGIGIVITVHLWKRYFREYEGETEERRRLRQENGTVHAIA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
106	N-linked (GlcNAc...) asparagine			UniProt
241	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 14** of 14 in total

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Pathway Name	Organism
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAF/MAP kinase cascade	Mus musculus
SHC1 events in EGFR signaling	Mus musculus
Signaling by EGFR	Mus musculus