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Cadherin-2A

Summary

UniProt ID: P33147
Gene Symbol: cdh2-a cdh2
Gene ID: 378518
Organism: Xenopus laevis (African clawed frog)

External Links

Re-Glyco: P33147

Annotation

Keyword: Calcium Cell adhesion Cell junction Cell membrane Cell projection Cleavage on pair of basic residues Glycoprotein Metal-binding Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
cell morphogenesis	IBA	GO_REF
cell morphogenesis	IEA	GO_REF
cell-cell junction assembly	IBA	GO_REF
cell-cell junction assembly	IEA	GO_REF
homophilic cell-cell adhesion	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction organization [inference]

synapse organization [inference]

synapse assembly

multicellular organismal process [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

maintenance of cell number [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	Reference
cytoplasm	IBA	GO_REF
cytoplasm	IEA	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	IEA	GO_REF GO_REF GO_REF
cell-cell junction	ISS	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

sarcolemma

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction

cell-cell contact zone [inference]

intercalated disc

cell projection [inference]

plasma membrane bounded cell projection [inference]

organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

apical part of cell

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GO Term	Evidence Code	Reference
calcium ion binding	ISS	GO_REF
calcium ion binding	IEA	GO_REF
beta-catenin binding	IBA	GO_REF
beta-catenin binding	IEA	GO_REF
cadherin binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

cell adhesion molecule binding [inference]

cadherin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MCRKEPFLLPTALCILAALVLHQGPVEALGGSRLCKTGFLEDVYHASVYRSVHEGQPLLNVKFTDCGADRRIHYETSNPTDFRIDGDGIVCASRTFDISPEQAEFLVYAQDEDTRELWHVTVKITLRPRHVQDLHQGFHKVREIKFSTQRKHNGLQRQKRDWVIPPINVPENARGTFPQELVGIRSDRDKSLSLRYSVTGPGADQPPLGVFIINPISGQLSVTKPLDREQIATFHLRAHAVDVNGNQVENPIDIVINVIDMNDNRPEFLHQIWNGTIPEGSKPGTYVMTVTAIDGDDPKQPNGMLRYKILSQTPASSSPNMFTINNETGDIITLAAGLDREKVQRYTLIIQATDMEGNPTYGLSNTATAVIAVTDVNDNPPEFTAMTFYGEVPENRVDVVVANLTVTDKDQPHTPAWNAVYRIVGGDGTGRFAIKTDANSNDGLVTVVKPIDYETKSTYILTVVAENQVELIRGIQYKPESTATVSVTIIDVNENPYFTPNPKLIRQEEGLFAGKLLTTFSAQDPDRYMQQTIRYSKLSDPANWLKIDPVNGFITTTAVLDRESIYVKNNMYNATFLATDSGIPPMSGTGTLQIYLLDINDNAPYVYPQEVEICDRPDPNAINITALDADINPNAGPFIFELPYSPMDIKKNWTVTRLSGDHAQLSLKIGSLDYGIYNIPIQITDSGNPAMSNTSYLRVKVCSCEHGYCSTTAPIIGTGLGTGAIIAILLCIIILLTLVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDTIKPVGIRRMDERPIHAEPQYPIRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGSDD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
274	N-linked (GlcNAc...) asparagine	UniProt
326	N-linked (GlcNAc...) asparagine	UniProt
403	N-linked (GlcNAc...) asparagine	UniProt
573	N-linked (GlcNAc...) asparagine	UniProt
623	N-linked (GlcNAc...) asparagine	UniProt
652	N-linked (GlcNAc...) asparagine	UniProt
693	N-linked (GlcNAc...) asparagine	UniProt