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DNA polymerase alpha subunit B

Summary

UniProt ID

P33611

Gene Symbol

Pola2

Gene ID

[18969]

Organism

Mus musculus (house mouse)

External Links

PubChem: P33611
The O-GlcNAc Database: P33611
Re-Glyco: P33611

Annotation

Keyword: DNA replication Direct protein sequencing Nucleus Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
DNA replication	ISO	GO_REF
DNA replication	IDA	PMID
DNA replication	IEA	GO_REF GO_REF
DNA replication, synthesis of primer	ISO	GO_REF
DNA replication, synthesis of primer	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA replication, synthesis of primer

intercellular transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

import into nucleus [inference]

protein import into nucleus

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
nucleus	IDA	PMID
nucleus	IEA	GO_REF
nucleoplasm	ISO	GO_REF
nucleoplasm	IEA	GO_REF
alpha DNA polymerase:primase complex	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

alpha DNA polymerase:primase complex

intracellular protein-containing complex [inference]

RNA polymerase complex [inference]

DNA-directed RNA polymerase complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

alpha DNA polymerase:primase complex

DNA polymerase complex [inference]

alpha DNA polymerase:primase complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

RNA polymerase complex [inference]

DNA-directed RNA polymerase complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

alpha DNA polymerase:primase complex

DNA polymerase complex [inference]

alpha DNA polymerase:primase complex

cellular anatomical structure [inference]

nucleoplasm

microtubule organizing center [inference]

ciliary basal body

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 2** entries
GO Term	Evidence Code	Reference
DNA binding	IEA	GO_REF
DNA-directed DNA polymerase activity	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

DNA polymerase activity [inference]

DNA-directed DNA polymerase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA polymerase activity [inference]

DNA-directed DNA polymerase activity

binding [inference]

nucleic acid binding [inference]

DNA binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAVSTQQLAEELQIFGLDYEDSLLEKLAELCVLYRQTEDGMVSELIAFCTSAGKTCLTVDILNSFEYEVLNKKLSKAWHSASKDSGHAGTRDIVSIQELIEAEEEEETLLSSYTTPSKGPLKRVSSTPETPLTKRSVAARSPRQLLSPSSFSPSATPSQKYTSRTNRGEVVTTFGSAQGLSWSGRGGSGSVSLKVVGDPEPLTGSYKAMFQQLMGVREVLTSKIEELGSELKEHHKIEAFTPLLVPAQEPVILLGQIGCDSNGKLNSKSVILEGDQEHSYGAQIPVDLSELKEYSLFPGQVVIMEGFNTTGRRLTATKLYEGVPLPFYQPTEEEGASEQTMVVVACGPYTTSDSITYDPLLDLIAIINRDQPDVCILFGPFLDAKHEQVENCKLTSPFEDVFKQCLRTVIEGTRSSGSHLVFVPSLRDVHHEPVYPQPPFTFSELSREDKKRVQFVSEPCSLSINGVMFGLTSTDLLFHIGAEEIFSSSGTSDRFSRVLKHILTQRSYYPLYPPHEDMAIDYENFYTYAQLPVTPDVFIVPSELRYFVKDIFGCVCVNPGRLTKGQVGGTFGRLYLRRQPKAMDGGGRQGLSVAAQVVRI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
229		40885482	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Activation of the pre-replicative complex	Mus musculus
DNA replication initiation	Mus musculus
Inhibition of replication initiation of damaged DNA by RB1/E2F1	Mus musculus
Polymerase switching	Mus musculus
Polymerase switching on the C-strand of the telomere	Mus musculus
Processive synthesis on the lagging strand	Mus musculus
Removal of the Flap Intermediate	Mus musculus
Telomere C-strand synthesis initiation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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International Collaboration

Acknowledgements