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Acetylcholine receptor-like protein cup-4

Summary

UniProt ID: P34271
Gene Symbol: C02C2.3 cup-4
Gene ID: 176104
Organism: Caenorhabditis elegans

External Links

Re-Glyco: P34271

Annotation

Keyword: Cytoplasmic vesicle Disulfide bond Endocytosis Glycoprotein Ligand-gated ion channel Receptor Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
endocytosis	IMP	PMID
chemical synaptic transmission
determination of adult lifespan	IMP	PMID
determination of adult lifespan	IGI	PMID
regulation of endocytosis	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

vesicle-mediated transport [inference]

endocytosis

transmembrane transport [inference]

monoatomic ion transmembrane transport

multicellular organismal process [inference]

determination of adult lifespan

response to stimulus [inference]

response to stress [inference]

response to caloric restriction

response to nutrient levels [inference]

response to caloric restriction

response to chemical [inference]

response to paraquat

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic ion transmembrane transport

vesicle-mediated transport [inference]

endocytosis

transmembrane transport [inference]

monoatomic ion transmembrane transport

import into cell [inference]

endocytosis

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of egg-laying behavior

positive regulation of reproductive process [inference]

positive regulation of egg-laying behavior

regulation of cellular process [inference]

regulation of cellular component organization [inference]

regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

regulation of egg-laying behavior [inference]

positive regulation of egg-laying behavior

positive regulation of behavior [inference]

positive regulation of egg-laying behavior

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of egg-laying behavior

regulation of reproductive process [inference]

regulation of egg-laying behavior [inference]

positive regulation of egg-laying behavior

positive regulation of reproductive process [inference]

positive regulation of egg-laying behavior

regulation of biological quality [inference]

regulation of membrane potential

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GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
cytoplasmic vesicle membrane	IDA	PMID
cytoplasmic vesicle membrane	IEA	GO_REF
cytoplasmic vesicle	IDA	PMID
neuron projection	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

postsynapse

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GO Term	Evidence Code	Reference
monoatomic ion channel activity	TAS	PMID
ion channel activity	TAS	PMID
ion channel activity	IEA	GO_REF
monoatomic ion channel activity	IEA	GO_REF
excitatory extracellular ligand-gated monoatomic ion channel activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

acetylcholine receptor activity

neurotransmitter receptor activity [inference]

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

postsynaptic neurotransmitter receptor activity [inference]

acetylcholine receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKIIIFVCFILIFYLPIQKKHVNSQQQGIDSDDGDAESFFNKSYSEHQSALEQKIFRGYNPKNRPMKNASFPTIVDVHWHIIHVSINQREQTMTVHGHIYMRWFDEFLVWDPKDFNNIQYARVKKWQVWQPKIKVSNSASGLGSAFDFSTSAHVIIQMMGKDRAKVEMYPTFSIKVGCAFDFTDYPYDLNKCAINLFSTSTMADVQLQNLYAIPPTLSFGWEEQKMKRIISDFKIQNVSSSALYYTNGNITSSAPITGFDLGSTWSMLAVTVSFVRHSPLFEAAVVTPCIVVASLISMTFFIDSLSSTFLLMMLHFYVQLIFLHDLVEKLPLSVSEIPFCIKLIGILMYTNGLTLVLHSSLLCGSYYKCPVPQQLNKIFVIEEYIPNTFKEKVQIKKEESNKSWRDLMKLIRPIIGFVLIILLICMFFVCLLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
41	N-linked (GlcNAc...) asparagine	UniProt
68	N-linked (GlcNAc...) asparagine	UniProt
237	N-linked (GlcNAc...) asparagine	UniProt
249	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Caenorhabditis elegans
Neurotransmitter receptors and postsynaptic signal transmission	Caenorhabditis elegans

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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International Collaboration

Acknowledgements