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Calnexin

Summary

UniProt ID: P34652
Gene Symbol: cnx-1 ZK632.6
Gene ID: 176390
Organism: Caenorhabditis elegans

External Links

PubChem: P34652
Re-Glyco: P34652

Annotation

Keyword: Calcium Chaperone Cytoplasm Cytoplasmic vesicle Developmental protein Disulfide bond Endoplasmic reticulum Glycoprotein Lectin Metal-binding Reference proteome Repeat Signal Stress response Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
protein folding	IBA	GO_REF
protein folding	IEA	GO_REF
response to heat	IEP	PMID
endoplasmic reticulum unfolded protein response	IEP	PMID
endoplasmic reticulum unfolded protein response	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

protein folding

signal transduction [inference]

intracellular signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

ERAD pathway

response to stimulus [inference]

response to stress [inference]

response to heat

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

ERAD pathway

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

response to chemical [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

ERAD pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

Displaying **all 5** entries
GO Term	Evidence Code	Reference
endoplasmic reticulum membrane	ISS	PMID
endoplasmic reticulum membrane	IEA	GO_REF
cytoplasmic vesicle	IEA	GO_REF
perinuclear region of cytoplasm	IDA	PMID
perinuclear region of cytoplasm	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

perinuclear region of cytoplasm

Displaying **all 5** entries
GO Term	Evidence Code	Reference
calcium ion binding	IDA	PMID
calcium ion binding	IBA	GO_REF
calcium ion binding	IEA	GO_REF
carbohydrate binding
unfolded protein binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

unfolded protein binding

carbohydrate binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVNRKWMYIFIQFLLVSSIRSDDDVFEDDEEEVTKGSDDKEEFVPSLFVAPKLSDKSTPNFFDYFPVGSKIGLTWIKSLAKKDDVDSDIAKYNGEWSIGAPTKVSIEGDLGLIVKTKARHHAIAAKLNTPFAFDANTFVVQYDIKFEEGQECGGGYLKLLSEGAEKDLANFQDKTAYTIMFGPDKCGATGKVHLIFRYKNPINGTISEYHANQPTTIGSTYWDDHNTHLFTLVVKPTGEYSVSVDGKSLYYGNMMSDVTPALTPPKQIFDETDLKPVDWDERENIEDESAVKPDDWDENEPQSVVDEAATKPYDWNEEENELIADPEAKKPQDWDEDMDGSWEAPLIDNPACKGLSGCGTWKAPTIKNPKYKGKWIRPKISNPAFKGKWTARLIDNPNYFEPKPFAGLAPITAVGIEMWTMSENILFDNILITSSEEDSSDVAKQTFYVKQKEEYRLAAATGNGNGFFQQIIDATNEKPWLWAVYILCVLLPLVAIGVFCFGKQSKPTPNFAKKSDAYSADDDRVPNLVDDDEEEIIGDEEDDVNQPGPSGSQSNPEPQDEEENAEQQSANSSQSSAAEEEDDEHVVPENEPVKPTEEFAKKSPKNTGGAKRRTARRGD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
203	N-linked (GlcNAc...) asparagine	16256074		UniProt
571	N-linked (GlcNAc...) asparagine	16256074		UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Calnexin/calreticulin cycle	Caenorhabditis elegans

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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