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Vesicular acetylcholine transporter unc-17

Summary

UniProt ID: P34711
Gene Symbol: ZC416.8 unc-17
Gene ID: 24105312
Organism: Caenorhabditis elegans

External Links

PubChem: P34711
Re-Glyco: P34711

Annotation

Keyword: Cytoplasmic vesicle Glycoprotein Neurotransmitter transport Reference proteome Synapse Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
nematode larval development	IMP	PMID
regulation of muscle contraction	IMP	PMID
chemical synaptic transmission	IBA	GO_REF
synaptic transmission, cholinergic	IMP	PMID
acetylcholine transport	ISS	PMID

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, cholinergic

multicellular organismal process [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

post-embryonic development [inference]

larval development [inference]

nematode larval development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

localization [inference]

establishment of localization [inference]

transport [inference]

organic cation transport [inference]

acetylcholine transport

nitrogen compound transport [inference]

acetylcholine transport

acetate ester transport [inference]

acetylcholine transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, cholinergic

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion

regulation of locomotion

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction

regulation of behavior [inference]

regulation of feeding behavior [inference]

regulation of eating behavior [inference]

regulation of nematode pharyngeal pumping

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
plasma membrane	NAS	PMID
synaptic vesicle	IDA	PMID
AP-1 adaptor complex	IBA	GO_REF
AP-2 adaptor complex	IBA	GO_REF
synaptic vesicle membrane	NAS	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

AP-type membrane coat adaptor complex [inference]

clathrin adaptor complex [inference]

plasma membrane protein complex [inference]

AP-2 adaptor complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell junction [inference]

synapse

excitatory synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

presynapse [inference]

terminal bouton

Displaying **all 4** entries
GO Term	Evidence Code	Reference
acetylcholine transmembrane transporter activity	ISS	PMID
acetylcholine transmembrane transporter activity	IMP	PMID
acetylcholine transmembrane transporter activity	IBA	GO_REF
xenobiotic transmembrane transporter activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

neurotransmitter transmembrane transporter activity [inference]

acetylcholine transmembrane transporter activity

xenobiotic transmembrane transporter activity

acetate ester transmembrane transporter activity [inference]

acetylcholine transmembrane transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGFNVPVINRDSEILKADAKKWLEQQDNQKKCVLVIVSIALLLDNMLYMVIVPIIPKYLRDIHNYQVTFEGYHNETSQLANGTYLVREVGGRINFLDEELELGWLFASKALLQIFVNPFSGYIIDRVGYEIPMILGLCTMFFSTAIFALGKSYGVLLFARSLQGFGSAFADTSGLAMIADRFTEENERSAALGIALAFISFGCLVAPPFGSVLYSLAGKPVPFLILSFVCLADAIAVFMVINPHRRGTDSHGEKVQGTPMWRLFMDPFIACCSGALIMANVSLAFLEPTITTWMSEMMPDTPGWLVGVIWLPPFFPHVLGVYVTVKMLRAFPHHTWAIAMVGLAMEGIACFAIPYTTSVMQLVIPLSFVCFGIALIDTSLLPMLGHLVDTRHVSVYGSVYAIADISYSLAYAFGPIIAGWIVTNWGFTALNIIIFATNVTYAPVLFLLRKVHSYDTLGAKGDTAEMTQLNSSAPAGGYNGKPEATTAESYQGWEDQQSYQNQAQIPNHAVSFQDSRPQAEFPAGYDPLNPQW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
74	N-linked (GlcNAc...) asparagine			UniProt
81	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Acetylcholine Neurotransmitter Release Cycle	Caenorhabditis elegans
Cargo recognition for clathrin-mediated endocytosis	Caenorhabditis elegans
Clathrin-mediated endocytosis	Caenorhabditis elegans

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements