GlyCosmos Portal

Submissions

Bone morphogenetic protein 8B

Summary

UniProt ID: P34820
Gene Symbol: BMP8 BMP8B
Gene ID: 656
Organism: Homo sapiens (human)

External Links

GlyGen: P34820
The Human Metabolome Database: HMDBP07473
The O-GlcNAc Database: P34820
RaftProt: P34820
Re-Glyco: P34820

Annotation

Keyword: Alternative splicing Chondrogenesis Cytokine Developmental protein Differentiation Disulfide bond Glycoprotein Growth factor Osteogenesis Proteomics identification Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
skeletal system development	TAS	PMID
ossification
cell differentiation
BMP signaling pathway	IBA	GO_REF
negative regulation of cell differentiation	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

cellular developmental process [inference]

cell differentiation

multicellular organismal process [inference]

ossification

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

cartilage development

system development [inference]

skeletal system development

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

regulation of cell differentiation [inference]

negative regulation of cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell differentiation

Displaying 1 entry
GO Term	Evidence Code	Reference
obsolete extracellular space

GO Hierarchy

cellular component

Displaying **all 3** entries
GO Term	Evidence Code	Reference
cytokine activity	ISS	GO_REF
cytokine activity	IBA	GO_REF
growth factor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTALPGPLWLLGLALCALGGGGPGLRPPPGCPQRRLGARERRDVQREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLYHAMAGDDDEDGAPAERRLGRADLVMSFVNMVERDRALGHQEPHWKEFRFDLTQIPAGEAVTAAEFRIYKVPSIHLLNRTLHVSMFQVVQEQSNRESDLFFLDLQTLRAGDEGWLVLDVTAASDCWLLKRHKDLGLRLYVETEDGHSVDPGLAGLLGQRAPRSQQPFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPDAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
107		38253038 39894887	G49108TO	The O-GlcNAc Database
158	N-linked (GlcNAc...) asparagine		G83460ZZ	UniProt GlyGen
343	N-linked (GlcNAc...) asparagine			UniProt GlyGen