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Ras-related protein Rab-6A

Summary

UniProt ID: P35279
Gene Symbol: MNCb-1660 Rab6 Rab6a
Gene ID: 19346
Organism: Mus musculus (house mouse)

External Links

GlyGen: P35279
The O-GlcNAc Database: P35279
RaftProt: P35279
O-GlcNAcAtlas: P35279
Re-Glyco: P35279

Annotation

Keyword: Acetylation Alternative splicing Cytoplasmic vesicle Direct protein sequencing ER-Golgi transport GTP-binding Golgi apparatus Hydrolase Magnesium Membrane Metal-binding Methylation Phosphoprotein Prenylation Protein transport Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
intracellular protein transport	TAS	PMID
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	ISS	GO_REF
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IBA	GO_REF
intra-Golgi vesicle-mediated transport	IBA	GO_REF
antigen processing and presentation

GO Hierarchy

biological process

immune system process [inference]

antigen processing and presentation

cellular process [inference]

intercellular transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

vesicle-mediated transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

Golgi vesicle transport [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to Golgi membrane

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport

protein localization to organelle [inference]

protein localization to Golgi apparatus

protein localization to Golgi membrane

protein localization to membrane [inference]

protein localization to Golgi membrane

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

protein transport [inference]

intracellular protein transport

vesicle-mediated transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

Golgi vesicle transport [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to Golgi membrane

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	Reference
Golgi membrane	ISS	GO_REF
Golgi membrane	ISO	GO_REF
Golgi membrane	EXP	PMID
Golgi membrane	IEA	GO_REF
acrosomal membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

nucleoplasm

microtubule organizing center [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

Golgi membrane

secretory granule membrane [inference]

acrosomal membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

endosome to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

endosome to plasma membrane transport vesicle

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

endosome to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

endosome to plasma membrane transport vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

endosome to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

endosome to plasma membrane transport vesicle

presynapse

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GO Term	Evidence Code	Reference
ATPase activator activity	ISO	GO_REF
GTPase activity	ISS	GO_REF
GTPase activity	ISO	GO_REF
GTPase activity	IEA	GO_REF
G protein activity	ISS	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

G protein activity

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

myosin binding [inference]

myosin V binding

enzyme binding [inference]

ATPase binding

protein domain specific binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

molecular function regulator activity [inference]

G protein activity

molecular function activator activity [inference]

ATPase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVNEGGCSC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
23		30016717 33300544	G49108TO	GlyGen The O-GlcNAc Database
31		30016717 33300544	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
COPI-independent Golgi-to-ER retrograde traffic	Mus musculus
Neutrophil degranulation	Mus musculus
RAB GEFs exchange GTP for GDP on RABs	Mus musculus
RAB geranylgeranylation	Mus musculus
Retrograde transport at the Trans-Golgi-Network	Mus musculus
TBC/RABGAPs	Mus musculus

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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Acknowledgements