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Type-2 angiotensin II receptor
Summary
- UniProt ID
- P35351
- Gene Symbol
- Agtr2
- Gene ID
- 24182
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Phosphoprotein Reference proteome Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| positive regulation of cytokine production | ||
| kidney development | ||
| regulation of systemic arterial blood pressure by circulatory renin-angiotensin | ||
| renin-angiotensin regulation of aldosterone production | ||
| angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| perinuclear region of cytoplasm |
| GO Term | Evidence Code | Reference |
|---|---|---|
| G-protein alpha-subunit binding | ||
| angiotensin type II receptor activity | ||
| angiotensin type II receptor activity | ||
| angiotensin type II receptor activity | ||
| angiotensin type II receptor activity |
GO Hierarchy
Sequence
MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (i) signalling events | Rattus norvegicus |
| Peptide ligand-binding receptors | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1591 | renovascular hypertension | |
| DOID:11049 | meconium aspiration syndrome | |
| DOID:784 | chronic kidney disease | |
| DOID:0050851 | glomerulosclerosis | |
| DOID:10763 | hypertension | |
| DOID:2921 | glomerulonephritis | |
| DOID:3827 | congenital diaphragmatic hernia |
