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Rhodopsin

Summary

UniProt ID

P35359

Gene Symbol

rho
zfo2

Gene ID

30295

Organism

Danio rerio (zebrafish)

External Links

PubChem: P35359
Re-Glyco: P35359

Annotation

Keyword: Cell projection Disulfide bond G-protein coupled receptor Glycoprotein Phosphoprotein Reference proteome Retinal protein Transmembrane helix Vision

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
G protein-coupled receptor signaling pathway	IBA	GO_REF
G protein-coupled receptor signaling pathway	IEA	GO_REF
visual perception	IEA	GO_REF
phototransduction	IBA	GO_REF
phototransduction	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled opsin signaling pathway

phototransduction

G protein-coupled opsin signaling pathway

light absorption [inference]

absorption of visible light

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

cellular response to light stimulus

G protein-coupled opsin signaling pathway

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

detection of abiotic stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

detection of abiotic stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled opsin signaling pathway

phototransduction

G protein-coupled opsin signaling pathway

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
photoreceptor outer segment	IDA	PMID
photoreceptor outer segment	IBA	GO_REF
photoreceptor outer segment	IEA	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

photoreceptor outer segment

membrane

plasma membrane

organelle membrane [inference]

photoreceptor disc membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
11-cis retinal binding	ISS	GO_REF
G protein-coupled photoreceptor activity	IDA	PMID
G protein-coupled photoreceptor activity	IBA	GO_REF
photoreceptor activity	NAS	PMID
photoreceptor activity	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinal binding

11-cis retinal binding

small molecule binding [inference]

vitamin binding [inference]

retinal binding

11-cis retinal binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled photoreceptor activity

photoreceptor activity

G protein-coupled photoreceptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNGTEGPAFYVPMSNATGVVRSPYEYPQYYLVAPWAYGLLAAYMFFLIITGFPVNFLTLYVTIEHKKLRTPLNYILLNLAIADLFMVFGGFTTTMYTSLHGYFVFGRLGCNLEGFFATLGGEMGLWSLVVLAIERWMVVCKPVSNFRFGENHAIMGVAFTWVMACSCAVPPLVGWSRYIPEGMQCSCGVDYYTRTPGVNNESFVIYMFIVHFFIPLIVIFFCYGRLVCTVKEAAAQQQESETTQRAEREVTRMVIIMVIAFLICWLPYAGVAWYIFTHQGSEFGPVFMTLPAFFAKTSAVYNPCIYICMNKQFRHCMITTLCCGKNPFEEEEGASTTASKTEASSVSSSSVSPA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
2	N-linked (GlcNAc...) asparagine	UniProt
15	N-linked (GlcNAc...) asparagine	UniProt
200	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Activation of the phototransduction cascade	Danio rerio
G alpha (i) signalling events	Danio rerio
Inactivation, recovery and regulation of the phototransduction cascade	Danio rerio
Opsins	Danio rerio
The canonical retinoid cycle in rods (twilight vision)	Danio rerio
VxPx cargo-targeting to cilium	Danio rerio

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements