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Tyrosine-protein phosphatase non-receptor type 1

Summary

UniProt ID

P35821

Gene Symbol

Ptpn1

Organism

Mus musculus (house mouse)

Annotation

Keyword

Acetylation
Endoplasmic reticulum
Membrane
Phosphoprotein
Protein phosphatase
Reference proteome
S-nitrosylation

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

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GO Term
peptidyl-tyrosine dephosphorylation
endoplasmic reticulum unfolded protein response
response to endoplasmic reticulum stress
platelet-derived growth factor receptor-beta signaling pathway
IRE1-mediated unfolded protein response
insulin receptor recycling
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
positive regulation of receptor catabolic process
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway

Displaying entries **1 - 10** of 11 in total

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GO Term
mitochondrial matrix
cytosol
endoplasmic reticulum
early endosome
sorting endosome
cytoplasmic side of endoplasmic reticulum membrane
cytoplasm
plasma membrane
protein-containing complex
mitochondrial crista

Displaying **all 8** entries
GO Term
protein kinase binding
protein phosphatase 2A binding
ephrin receptor binding
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
insulin receptor binding
zinc ion binding
receptor tyrosine kinase binding

Annotation information from UniProt.

Sequence

MEMEKEFEEIDKAGNWAAIYQDIRHEASDFPCKVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQQEEKEMVFDDTGLKLTLISEDVKSYYTVRQLELENLTTKETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSREDLDLPPEHVPPPPRPPKRTLEPHNGKCKELFSSHQWVSEETCGDEDSLAREEGRAQSSAMHSVSSMSPDTEVRRRMVGGGLQSAQASVPTEEELSSTEEEHKAHWPSHWKPFLVNVCMATLLATGAYLCYRVCFH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Growth hormone receptor signaling	Mus musculus
Insulin receptor recycling	Mus musculus
Integrin signaling	Mus musculus
Negative regulation of MET activity	Mus musculus
PTK6 Down-Regulation	Mus musculus
Regulation of IFNA/IFNB signaling	Mus musculus