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MIRAGE
Vascular endothelial growth factor receptor 2
Summary
- UniProt ID
- P35918
- Gene Symbol
-
- Flk-1
- Flk1
- Kdr
- Gene ID
- 16542
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003600
- GlyGen
- P35918
- PubChem
- P35918
- Re-Glyco
- P35918
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Angiogenesis
- Cell junction
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Developmental protein
- Differentiation
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Immunoglobulin domain
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| membrane raft |
| sorting endosome |
| extracellular region |
| nucleus |
| cytoplasm |
| plasma membrane |
| cell junction |
| anchoring junction |
Sequence
MESKALLAVALWFCVETRAASVGLPGDFLHPPKLSTQKDILTILANTTLQITCRGQRDLDWLWPNAQRDSEERVLVTECGGGDSIFCKTLTIPRVVGNDTGAYKCSYRDVDIASTVYVYVRDYRSPFIASVSDQHGIVYITENKNKTVVIPCRGSISNLNVSLCARYPEKRFVPDGNRISWDSEIGFTLPSYMISYAGMVFCEAKINDETYQSIMYIVVVVGYRIYDVILSPPHEIELSAGEKLVLNCTARTELNVGLDFTWHSPPSKSHHKKIVNRDVKPFPGTVAKMFLSTLTIESVTKSDQGEYTCVASSGRMIKRNRTFVRVHTKPFIAFGSGMKSLVEATVGSQVRIPVKYLSYPAPDIKWYRNGRPIESNYTMIVGDELTIMEVTERDAGNYTVILTNPISMEKQSHMVSLVVNVPPQIGEKALISPMDSYQYGTMQTLTCTVYANPPLHHIQWYWQLEEACSYRPGQTSPYACKEWRHVEDFQGGNKIEVTKNQYALIEGKNKTVSTLVIQAANVSALYKCEAINKAGRGERVISFHVIRGPEITVQPAAQPTEQESVSLLCTADRNTFENLTWYKLGSQATSVHMGESLTPVCKNLDALWKLNGTMFSNSTNDILIVAFQNASLQDQGDYVCSAQDKKTKKRHCLVKQLIILERMAPMITGNLENQTTTIGETIEVTCPASGNPTPHITWFKDNETLVEDSGIVLRDGNRNLTIRRVRKEDGGLYTCQACNVLGCARAETLFIIEGAQEKTNLEVIILVGTAVIAMFFWLLLVIVLRTVKRANEGELKTGYLSIVMDPDELPLDERCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRGKRNEFVPYKSKGARFRQGKDYVGELSVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEASEELYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPSFSELVEHLGNLLQANAQQDGKDYIVLPMSETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDNTAGISHYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDSQTDSGMVLASEELKTLEDRNKLSPSFGGMMPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSDEAGLLKMVDAAVHADSGTTLRSPPV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 46 | N-linked (GlcNAc...) asparagine | |||
| 98 | N-linked (GlcNAc...) asparagine | |||
| 145 | N-linked (GlcNAc...) asparagine | |||
| 160 | N-linked (GlcNAc...) asparagine | |||
| 247 | N-linked (GlcNAc...) asparagine | |||
| 320 | N-linked (GlcNAc...) asparagine |
|
||
| 376 | N-linked (GlcNAc...) asparagine | |||
| 397 | N-linked (GlcNAc...) asparagine | |||
| 509 | N-linked (GlcNAc...) asparagine | |||
| 521 | N-linked (GlcNAc...) asparagine |
G24748EV
G80920RR
G62765YT
G62595EF
G27126ED
G09197ZW
G25987BV
G02815KT
G65363KE
G10486CT
G15038BD
G25079LO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neurophilin interactions with VEGF and VEGFR | Mus musculus |
| VEGF binds to VEGFR leading to receptor dimerization | Mus musculus |
| VEGFA-VEGFR2 Pathway | Mus musculus |
| VEGFR2 mediated cell proliferation | Mus musculus |
