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MIRAGE
Epithelial sodium channel subunit alpha
Summary
- UniProt ID
- P37089
- Gene Symbol
-
- RCNaCh
- RCNaCh1
- Renac
- Scnn1a
- Gene ID
- 25122
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Flagellum
- Glycoprotein
- Reference proteome
- Sodium channel
- Taste
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| membrane |
| motile cilium |
| cytosol |
| external side of plasma membrane |
| apical plasma membrane |
| acrosomal vesicle |
| cortical actin cytoskeleton |
| extracellular exosome |
| GO Term |
|---|
| actin binding |
| ligand-gated sodium channel activity |
| WW domain binding |
Sequence
MLDHTRAPELNIDLDLHASNSPKGSMKGNQFKEQDPCPPQPMQGLGKGDKREEQGLGPEPSAPRQPTEEEEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYLSYPVSLNINLNSDKLVFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGARRRSSRDLLGAFPHPLQRLRTPPPPYSGRTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLSDTSPALEEEALGNFIFTCRFNQAPCNQANYSKFHHPMYGNCYTFNDKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKEALDSLGGNYGDCTENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYPKPKGVEFCDYRKQSSWGYCYYKLQGAFSLDSLGCFSKCRKPCSVINYKLSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLLVITLLMLLRRFRSRYWSPGRGARGAREVASTPASSFPSRFCPHPTSPPPSLPQQGMTPPLALTAPPPAYATLGPSAPPLDSAAPDCSACALAAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 190 | N-linked (GlcNAc...) asparagine |
|
||
| 259 | N-linked (GlcNAc...) asparagine |
|
||
| 320 | N-linked (GlcNAc...) asparagine |
|
||
| 339 | N-linked (GlcNAc...) asparagine |
|
||
| 424 | N-linked (GlcNAc...) asparagine |
|
||
| 538 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Sensory perception of salty taste | Rattus norvegicus |
| Stimuli-sensing channels | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1184 | nephrotic syndrome |
