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Transketolase

Summary

UniProt ID: P40142
Gene Symbol: Tkt
Gene ID: 21881
Organism: Mus musculus (house mouse)

External Links

GlyGen: P40142
PubChem: P40142
RaftProt: P40142
Re-Glyco: P40142

Annotation

Keyword: Acetylation Calcium Direct protein sequencing Isopeptide bond Magnesium Metal-binding Phosphoprotein Reference proteome Thiamine pyrophosphate Transferase Ubl conjugation

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
pentose-phosphate shunt	ISO	GO_REF GO_REF
pentose-phosphate shunt	IDA	PMID PMID
pentose-phosphate shunt	IEA	GO_REF
pentose-phosphate shunt, non-oxidative branch	ISO	GO_REF
pentose-phosphate shunt, non-oxidative branch	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pentose-phosphate shunt, non-oxidative branch

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

glyceraldehyde-3-phosphate metabolic process [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

D-xylulose 5-phosphate metabolic process [inference]

D-xylulose 5-phosphate biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

glyceraldehyde-3-phosphate metabolic process [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

D-xylulose 5-phosphate metabolic process [inference]

D-xylulose 5-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

carbohydrate derivative metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

D-xylulose 5-phosphate metabolic process [inference]

D-xylulose 5-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of growth

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GO Term	Evidence Code	Reference
nucleoplasm	ISO	GO_REF
nucleoplasm	IEA	GO_REF
peroxisome	ISO	GO_REF
endoplasmic reticulum membrane	ISO	GO_REF
cytosol	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

myelin sheath

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nuclear body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular membraneless organelle [inference]

nuclear body

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
magnesium ion binding	ISO	GO_REF GO_REF
magnesium ion binding	IEA	GO_REF
transketolase activity	ISO	GO_REF GO_REF
transketolase activity	IDA	PMID PMID
transketolase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transketolase or transaldolase activity [inference]

transketolase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

carbohydrate binding

monosaccharide binding

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

metal ion binding [inference]

monosaccharide binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDIYQKRCEAFGWHTIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQSKKKILATPPQEDAPSVDIANIRMPTPPSYKVGDKIATRKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites