T-lymphocyte activation antigen CD86
| GO Term | Evidence Code | Reference |
|---|---|---|
| toll-like receptor signaling pathway | ||
| adaptive immune response |
|
|
| positive regulation of immunoglobulin production | ||
| negative regulation of T cell anergy | ||
| immune response |
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane | ||
| external side of plasma membrane |
| GO Term | Evidence Code | Reference |
|---|---|---|
| signaling receptor binding | ||
| receptor ligand activity | ||
| receptor ligand activity |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 33 |
|
|
||
| 47 |
|
|
||
| 92 |
|
|
||
| 135 |
|
|
||
| 146 |
|
|
||
| 154 |
|
|
||
| 175 |
|
|
||
| 190 |
|
|
||
| 231 |
|
|
| Pathway Name | Organism |
|---|---|
| CD28 co-stimulation | Mus musculus |
| CD28 dependent PI3K/Akt signaling | Mus musculus |
| CD28 dependent Vav1 pathway | Mus musculus |
| Co-inhibition by CTLA4 | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: April 6, 2026