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Signal transducer and activator of transcription 3

Summary

UniProt ID

P42227

Gene Symbol

Stat3
Aprf

Organism

Mus musculus (house mouse)

External Links

GlyGen: P42227
PubChem: P42227
The O-GlcNAc Database: P42227
RaftProt: P42227
O-GlcNAcAtlas: P42227

Annotation

Keyword

3D-structure
Acetylation
Activator
Acute phase
Alternative splicing
Cytoplasm
DNA-binding
Direct protein sequencing
Nucleus
Phosphoprotein
Reference proteome
SH2 domain
Transcription regulation

Gene Ontology (GO)

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GO Term
negative regulation of autophagy
response to estradiol
positive regulation of interleukin-1 beta production
positive regulation of interleukin-10 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
response to cytokine
somatic stem cell population maintenance
regulation of multicellular organism growth

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GO Term
protein-containing complex
glutamatergic synapse
cytoplasm

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GO Term
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
nuclear receptor activity
sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
protein phosphatase binding
signaling adaptor activity
primary miRNA binding
acetylation-dependent protein binding

Annotation information from UniProt.

Sequence

MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	GlyTouCan ID	Source
401	G97993TU	GlyGen
714	G49108TO	GlyGen The O-GlcNAc Database
716	G49108TO	GlyGen
717	G49108TO	GlyGen The O-GlcNAc Database
719	G49108TO	GlyGen The O-GlcNAc Database
721	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Downstream signal transduction	Mus musculus
Interleukin-10 signaling	Mus musculus
Interleukin-15 signaling	Mus musculus
Interleukin-20 family signaling	Mus musculus
Interleukin-21 signaling	Mus musculus
Interleukin-23 signaling	Mus musculus
Interleukin-27 signaling	Mus musculus
Interleukin-35 Signalling	Mus musculus
Interleukin-37 signaling	Mus musculus
Interleukin-4 and Interleukin-13 signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements