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E3 ubiquitin-protein ligase NEDD4

Summary

UniProt ID: P46935
Gene Symbol: Nedd4 Kiaa0093 Nedd-4 Nedd4-1 Nedd4a Rpf1
Gene ID: 17999
Organism: Mus musculus (house mouse)

External Links

GlyGen: P46935
PubChem: P46935
The O-GlcNAc Database: P46935
RaftProt: P46935
O-GlcNAcAtlas: P46935
Re-Glyco: P46935

Annotation

Keyword: 3D-structure Cell membrane Cytoplasm Isopeptide bond Neurogenesis Nucleus Phosphoprotein Reference proteome Repeat Transferase Ubl conjugation Ubl conjugation pathway

Gene Ontology (GO)

Displaying entries **1 - 5** of 74 in total

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GO Term	Evidence Code	Reference
negative regulation of transcription by RNA polymerase II	ISO	GO_REF
negative regulation of transcription by RNA polymerase II	IMP	PMID
negative regulation of transcription by RNA polymerase II	IEA	GO_REF
adaptive immune response	IMP	PMID
outflow tract morphogenesis	IMP	PMID

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

signal transduction [inference]

hormone-mediated signaling pathway [inference]

steroid hormone receptor signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

nuclear receptor-mediated signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

receptor catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

receptor catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

protein metabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

receptor metabolic process [inference]

receptor catabolic process

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

protein metabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

cell junction organization [inference]

synapse organization [inference]

neuromuscular junction development

viral process [inference]

viral budding

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

tissue development [inference]

mesenchyme development [inference]

endocardial cushion development

biological process involved in interspecies interaction between organisms [inference]

formation of structure involved in a symbiotic process

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

cellular response to stress [inference]

cellular response to DNA damage stimulus

immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to organelle [inference]

protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of localization [inference]

transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission [inference]

regulation of protein catabolic process at postsynapse, modulating synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

negative regulation of sodium ion transport

regulation of potassium ion transport [inference]

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

regulation of postsynaptic neurotransmitter receptor internalization

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendrite morphogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway [inference]

steroid hormone receptor signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

nuclear receptor-mediated signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission [inference]

regulation of protein catabolic process at postsynapse, modulating synaptic transmission

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

regulation protein catabolic process at synapse [inference]

regulation protein catabolic process at postsynapse

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

regulation of postsynaptic neurotransmitter receptor internalization

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of dendrite development [inference]

regulation of dendrite morphogenesis

regulation of synapse organization

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

regulation of postsynaptic neurotransmitter receptor internalization

regulation of biological quality [inference]

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GO Term	Evidence Code	Reference
ubiquitin ligase complex	IPI	PMID
chromatin	ISO	GO_REF
chromatin	IEA	GO_REF
nucleus	ISS	GO_REF
nucleus	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex

intracellular protein-containing complex [inference]

ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex

cellular anatomical structure [inference]

cytoplasm

cell cortex

cytosol

postsynaptic cytosol

membrane

plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	Reference
ubiquitin-protein transferase activity	ISO	GO_REF GO_REF
ubiquitin-protein transferase activity	IEA	GO_REF GO_REF
channel inhibitor activity	ISO	GO_REF
channel inhibitor activity	IEA	GO_REF
potassium channel inhibitor activity	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

adrenergic receptor binding [inference]

beta-2 adrenergic receptor binding

glutamate receptor binding [inference]

ionotropic glutamate receptor binding

enzyme binding

RNA polymerase binding

protein domain specific binding

ubiquitin-like protein binding [inference]

ubiquitin binding

transmembrane transporter binding

phosphoprotein binding [inference]

protein phosphorylated amino acid binding [inference]

proline-rich region binding

molecular function regulator activity [inference]

molecular function inhibitor activity [inference]

transporter inhibitor activity [inference]

channel inhibitor activity

ion channel inhibitor activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

channel inhibitor activity

ion channel inhibitor activity [inference]

ion channel regulator activity [inference]

ion channel inhibitor activity [inference]

potassium channel regulator activity [inference]

potassium channel inhibitor activity

sodium channel regulator activity [inference]

sodium channel inhibitor activity

transporter inhibitor activity [inference]

channel inhibitor activity

ion channel inhibitor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSSDMAADESEAPVLSEDEVWEFCLDKTEDGGGSPGSDVTDTCEPPCGCWELNPNSLEEEHVLFTADPYLELHNDDTRVVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILFRVLPQRHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLPKNGSEDENADQAEELEPGWVVLDQPDAATHLPHPPEPSPLPPGWEERQDVLGRTYYVNHESRRTQWKRPSPDDDLTDEDNDDMQLQAQRAFTTRRQISEDVDGPDNRESPENWEIVREDENTEYSGQAVQSPPSGHIDVQTHLAEEFNTRLAVCGNPATSQPVTSSNHSSRGGSLQTCIFEEQPTLPVLLPTSSGLPPGWEEKQDDRGRSYYVDHNSKTTTWSKPTMQDDPRSKIPAHLRGKTDSNDLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDPRLQNVAITGPAVPYSRDYKRKYEFFRRKLKKQTDIPNKFEMKLRRANILEDSYRRIMGVKRADLLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPTELDLRFIIDEELFGQTHQHELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFDGVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	PubMed ID	GlyTouCan ID	Source
370	21540332 22517741 22645316 24788674 25153642 28528544 33300544 34887587 36852467 37507081 39627609 40885482	G49108TO	The O-GlcNAc Database
371	21540332 22517741 22645316 24788674 25153642 28528544 33300544 34887587 36852467 37507081 39627609 40885482	G49108TO	GlyGen The O-GlcNAc Database
375	21540332 22517741 22645316 24788674 25153642 28528544 33300544 34887587 36852467 37507081 39627609 40885482	G49108TO	GlyGen The O-GlcNAc Database
376	21540332 22517741 22645316 24788674 25153642 28528544 33300544 34887587 36852467 37507081 39627609 40885482	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Antigen processing: Ubiquitination & Proteasome degradation	Mus musculus
Downregulation of ERBB4 signaling	Mus musculus
ISG15 antiviral mechanism	Mus musculus
Regulation of PTEN localization	Mus musculus
Regulation of PTEN stability and activity	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements