RAC-alpha serine/threonine-protein kinase
| GO Term | Evidence Code | Reference |
|---|---|---|
| osteoblast differentiation | ||
| maternal placenta development | ||
| positive regulation of endothelial cell proliferation | ||
| positive regulation of endothelial cell proliferation | ||
| cell migration involved in sprouting angiogenesis |
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein kinase activity | ||
| protein kinase activity | ||
| protein kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 126 |
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| 129 |
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| 305 |
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| 312 |
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| 473 |
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| Pathway Name | Organism |
|---|---|
| AKT phosphorylates targets in the cytosol | Rattus norvegicus |
| AKT phosphorylates targets in the nucleus | Rattus norvegicus |
| AKT-mediated inactivation of FOXO1A | Rattus norvegicus |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | Rattus norvegicus |
| CD28 dependent PI3K/Akt signaling | Rattus norvegicus |
| Co-inhibition by CTLA4 | Rattus norvegicus |
| Cyclin A:Cdk2-associated events at S phase entry | Rattus norvegicus |
| Cyclin E associated events during G1/S transition | Rattus norvegicus |
| Deactivation of the beta-catenin transactivating complex | Rattus norvegicus |
| Downregulation of ERBB2:ERBB3 signaling | Rattus norvegicus |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:10763 | hypertension | |
| DOID:9976 | heroin dependence | |
| DOID:1875 | impotence | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:5844 | myocardial infarction |
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Last updated: April 6, 2026