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ATP-dependent 6-phosphofructokinase, muscle type

Summary

UniProt ID

P47857

Gene Symbol

Pfk-m
Pfka
Pfkm

Gene ID

18642

Organism

Mus musculus (house mouse)

External Links

GlyGen: P47857
PubChem: P47857
RaftProt: P47857
Re-Glyco: P47857

Annotation

Keyword

ATP-binding
Acetylation
Allosteric enzyme
Alternative splicing
Cytoplasm
Direct protein sequencing
Flagellum
Glycolysis
Glycoprotein
Hydroxylation
Kinase
Magnesium
Metal-binding
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
cytosol
apical plasma membrane
6-phosphofructokinase complex
nucleus
sperm principal piece

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
glycogen catabolic process
positive regulation of insulin secretion
glucose homeostasis
positive regulation of transcription by RNA polymerase II
muscle cell cellular homeostasis
glycolytic process through fructose-6-phosphate
glycolysis from storage polysaccharide through glucose-1-phosphate
fructose 6-phosphate metabolic process
canonical glycolysis

Displaying **all 7** entries
GO Term
6-phosphofructokinase activity
fructose binding
metal ion binding
phosphofructokinase activity
ATP binding
kinase binding
identical protein binding

Annotation information from UniProt.

Sequence

MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLNDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWEVYKLLAHVRPPVSKGGLHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKNLEQISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSIGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVTELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHISRKRSGEAAV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites