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MIRAGE
Sodium- and chloride-dependent betaine transporter
Summary
- UniProt ID
- P48056
- Gene Symbol
- Slc6a12
- Gene ID
- 50676
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Cell membrane Glycoprotein Neurotransmitter transport Phosphoprotein Reference proteome Symport Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| neurotransmitter transport | ||
| neurotransmitter transport | ||
| amino acid transport | ||
| intracellular water homeostasis | ||
| monocarboxylic acid transport |
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| basolateral plasma membrane |
| GO Term | Evidence Code | Reference |
|---|---|---|
| gamma-aminobutyric acid:sodium:chloride symporter activity | ||
| gamma-aminobutyric acid:sodium:chloride symporter activity | ||
| gamma-aminobutyric acid:sodium:chloride symporter activity | ||
| gamma-aminobutyric acid:sodium:chloride symporter activity | ||
| gamma-aminobutyric acid:sodium:chloride symporter activity |
GO Hierarchy
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
active transmembrane transporter activity [inference]
Sequence
MDRKVTVHEDGCPVVSWVPEEGEMMDQKDKDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTEHCVDFLNYSSTRAASYSENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSILGFMAQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFLMLLFLGLDSQFVCMECLVTASMDMFPQQLRKRGRRELLILAVAIVCYLMGLLLVTEGGMYIFQLFDYYASSGICLLFLSLFEVICIGWVYGADRFYDNVEDMIGYRPWPLVKISWLFLTPGLCLATFFFSLSKYTPLKYNNVYIYPSWGYSIGWLLAFSSMACVPLFIIITLLKTQGSFKKRLQRLITPDPSLPQPGRRSPQDGSSAQNCSTSPVKQELIAWEKETHL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Amino acid transport across the plasma membrane | Rattus norvegicus |
| Creatine metabolism | Rattus norvegicus |
| Reuptake of GABA | Rattus norvegicus |
