Prelamin-A/C [Cleaved into: Lamin-A/C]

Summary
UniProt ID
P48678
Gene Symbol
Lmna Lmn1
Gene ID
16905
Organism
Mus musculus (house mouse)
GlyGen
P48678
PubChem
P48678
The O-GlcNAc Database
P48678
RaftProt
P48678
O-GlcNAcAtlas
P48678
Re-Glyco
P48678
Annotation
Keyword
3D-structure Acetylation Alternative splicing Coiled coil Direct protein sequencing Glycoprotein Intermediate filament Isopeptide bond Methylation Nucleus Phosphoprotein Prenylation Reference proteome Ubl conjugation
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 30 in total
GO Term Evidence Code Reference
nucleus
nucleus
nucleus
nuclear envelope
nuclear envelope
Sequence
METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINSTGEEVAMRKLVRSLTMVEDNEDDDEDGEELLHHHRGSHCSGSGDPAEYNLRSRTVLCGTCGQPADKAAGGAGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRSQSSQNCSIM
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Breakdown of the nuclear lamina Mus musculus
Depolymerization of the Nuclear Lamina Mus musculus
Initiation of Nuclear Envelope (NE) Reformation Mus musculus
Nuclear Envelope Breakdown Mus musculus
Disease
Displaying all 7 entries
DO ID Disease Name Source
DOID:3911 progeria
DOID:9164 achalasia
DOID:10754 otitis media
DOID:0110425 dilated cardiomyopathy 1A
DOID:0110156 Charcot-Marie-Tooth disease type 2B1
DOID:0110640 congenital muscular dystrophy due to LMNA mutation
DOID:11726 Emery-Dreifuss muscular dystrophy

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026