Prelamin-A/C [Cleaved into: Lamin-A/C]
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein import into nucleus | ||
| nucleus organization | ||
| nucleus organization | ||
| nuclear envelope organization | ||
| nuclear envelope organization |
| GO Term | Evidence Code | Reference |
|---|---|---|
| structural constituent of cytoskeleton | ||
| structural constituent of cytoskeleton | ||
| structural constituent of cytoskeleton | ||
| protein phosphatase 1 binding | ||
| identical protein binding |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 456 |
|
|||
| 611 |
|
|||
| 613 |
|
|||
| 614 |
|
|||
| 626 |
|
|
||
| 629 |
|
|||
| 644 |
|
| Pathway Name | Organism |
|---|---|
| Breakdown of the nuclear lamina | Mus musculus |
| Depolymerization of the Nuclear Lamina | Mus musculus |
| Initiation of Nuclear Envelope (NE) Reformation | Mus musculus |
| Nuclear Envelope Breakdown | Mus musculus |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3911 | progeria | |
| DOID:9164 | achalasia | |
| DOID:10754 | otitis media | |
| DOID:0110425 | dilated cardiomyopathy 1A | |
| DOID:0110156 | Charcot-Marie-Tooth disease type 2B1 | |
| DOID:0110640 | congenital muscular dystrophy due to LMNA mutation | |
| DOID:11726 | Emery-Dreifuss muscular dystrophy |
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: April 6, 2026