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M-phase inducer phosphatase 1

Summary

UniProt ID: P48964
Gene Symbol: Cdc25a Cdc25m3
Gene ID: 12530
Organism: Mus musculus (house mouse)

External Links

PubChem: P48964
The O-GlcNAc Database: P48964
Re-Glyco: P48964

Annotation

Keyword: Mitosis Phosphoprotein Protein phosphatase Reference proteome Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	Reference
G1/S transition of mitotic cell cycle	ISO	GO_REF
G2/M transition of mitotic cell cycle	ISO	GO_REF
G2/M transition of mitotic cell cycle	IBA	GO_REF
G2/M transition of mitotic cell cycle	IEA	GO_REF
nuclear envelope organization	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

cell cycle G2/M phase transition [inference]

G2/M transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic cell cycle process [inference]

mitotic nuclear membrane disassembly

mitotic cell cycle phase transition [inference]

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

membrane disassembly [inference]

nuclear membrane disassembly [inference]

mitotic nuclear membrane disassembly

membrane organization [inference]

nuclear envelope organization

membrane disassembly [inference]

nuclear membrane disassembly [inference]

mitotic nuclear membrane disassembly

nuclear membrane organization [inference]

nuclear membrane disassembly [inference]

mitotic nuclear membrane disassembly

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of cholangiocyte proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of cholangiocyte proliferation

regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of cholangiocyte proliferation

regulation of cholangiocyte proliferation [inference]

positive regulation of cholangiocyte proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of cholangiocyte proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle process [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of meiotic cell cycle phase transition [inference]

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

regulation of meiotic cell cycle phase transition [inference]

regulation of G2/MI transition of meiotic cell cycle [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic cell cycle phase transition [inference]

positive regulation of G2/MI transition of meiotic cell cycle

Displaying **all 4** entries
GO Term	Evidence Code	Reference
nucleus	IDA	PMID
nucleus	IBA	GO_REF
cytoplasm	IDA	PMID
cytoplasm	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
phosphoprotein phosphatase activity	ISS	GO_REF
phosphoprotein phosphatase activity	ISO	GO_REF GO_REF
phosphoprotein phosphatase activity	IEA	GO_REF
protein tyrosine phosphatase activity	ISS	GO_REF
protein tyrosine phosphatase activity	ISO	GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein-folding chaperone binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MELGPEPPHRRRLFFACSPTPAPQPTGKMLFGASAAGGLSPVTNLTVTMDQLEGLGSDCEKMEVRNNSSLQRMGSSESTDSGFCLDSPGPLDSKENLEISLTRINSLPQKLLGCSPALKRSHSDSLDHDTFHLIDQDENKENEAFEFKKPIRPASRHIYEESKDPFTHRQNSAPARMLSSNESESGNFSPLFIPQSPVKATLSDEDDGFIDLLDGENMKNDEETPSCMASLWTAPLVMRRPANLADRCGLFDSPSPCGSSTRAVLKRADRSHEEPPRGTKRRKSVPSPVKAKADVPEPAQLPSQSLSLMSSPKGTIENILDSDPRDLIGDFSKGYLFNTVSGKHQDLKYISPEIMASVLNGKFAGLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKNPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
100		40885482	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Activation of ATR in response to replication stress	Mus musculus
Cyclin A/B1/B2 associated events during G2/M transition	Mus musculus
Cyclin A:Cdk2-associated events at S phase entry	Mus musculus
Cyclin E associated events during G1/S transition	Mus musculus
Ub-specific processing proteases	Mus musculus
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	Mus musculus