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MIRAGE
Bone morphogenetic protein 2
Summary
- UniProt ID
- P49001
- Gene Symbol
- Bmp-2 Bmp2
- Gene ID
- 29373
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Chondrogenesis Cleavage on pair of basic residues Cytokine Developmental protein Differentiation Disulfide bond Glycoprotein Growth factor Osteogenesis Phosphoprotein Reference proteome Secreted Signal
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| MAPK cascade |
|
|
| osteoblast differentiation | ||
| osteoblast differentiation | ||
| branching involved in ureteric bud morphogenesis |
GO Hierarchy
- positive regulation of cartilage development
- positive regulation of cartilage development
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of cell communication [inference]
positive regulation of cell differentiation [inference]
positive regulation of response to stimulus [inference]
positive regulation of developmental process [inference]
positive regulation of cell differentiation [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
positive regulation of cell differentiation [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of hormone biosynthetic process [inference]
regulation of lipid biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of hormone metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of cell communication [inference]
positive regulation of cell differentiation [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytokine activity | ||
| cytokine activity | ||
| growth factor activity | ||
| growth factor activity | ||
| growth factor activity |
Sequence
MVAGTRCLLVLLLPQVLLGGAAGLIPELGRKKFAGASRPLSRPSEDVLSEFELRLLSMFGLKQRPTPSKDVVVPPYMLDLYRRHSGQPGALAPDHRLERAASRANTVLSFHHEEAIEELSEMSGKTSRRFFFNLSSVPTDEFLTSAELQIFREQMQEALGNSSFQHRINIYEIIKPATASSKFPVTRLLDTRLVTQNTSQWESFDVTPAVMRWTAQGHTNHGFVVEVAHLEEKPGVSKRHVRISRSLHQDEHSWSQVRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Molecules associated with elastic fibres | Rattus norvegicus |
| Signaling by BMP | Rattus norvegicus |
