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Secretory phospholipase A2 receptor

Summary

UniProt ID

P49259

Gene Symbol

PLA2R1

Gene ID

317777

Organism

Bos taurus (domestic cattle)

External Links

PubChem: P49259
Re-Glyco: P49259

Annotation

Keyword: Cell membrane Direct protein sequencing Disulfide bond Endocytosis Glycoprotein Lectin Receptor Reference proteome Repeat Secreted Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
positive regulation of cytokine production	ISS	GO_REF
receptor-mediated endocytosis	ISS	GO_REF
receptor-mediated endocytosis	IBA	GO_REF
receptor-mediated endocytosis	IEA	GO_REF
positive regulation of DNA damage response, signal transduction by p53 class mediator	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

reactive oxygen species metabolic process

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cell cycle process [inference]

replicative senescence

cellular senescence [inference]

stress-induced premature senescence [inference]

oxidative stress-induced premature senescence

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of organic acid transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of secretion [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of fatty acid transport [inference]

regulation of icosanoid secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of arachidonate secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of organic acid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of secretion [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of fatty acid transport [inference]

positive regulation of icosanoid secretion [inference]

positive regulation of arachidonic acid secretion

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of cellular response to stress [inference]

regulation of DNA damage response, signal transduction by p53 class mediator [inference]

positive regulation of DNA damage response, signal transduction by p53 class mediator

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

Displaying **all 5** entries
GO Term	Evidence Code	Reference
extracellular region	IEA	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
signaling receptor complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
carbohydrate binding
signaling receptor activity	ISS	GO_REF
phospholipase binding	ISS	GO_REF
phospholipase binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

phospholipase binding

carbohydrate binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPLLSLSLLLLLLQVPAGSAETAAWAVTPERLREWQDKGIFIIQSENLEKCIQASKSTLTLENCKPPNKYMLWKWVSNHRLFNIGGSGCLGLNVSSPEQPLSIYECDSTHVSLKWHCNKKTITGPLQYLVQVKQDNTLVASRKYLHKWVSYMSGGGGICDYLHKDLYTIKGNAHGTPCMFPFQYNQQWHHECTREGREDNLLWCATTSRYERDEKWGFCPDPTSTEVGCDAVWEKDLHSRICYQFNLLSSLSWSEAHSSCQMQGAALLSIADETEENFVRKHLGSEAVEVWMGLNQLDEDAGWQWSDRTPLNYLNWKPEINFEPFVEYHCGTFNAFMPKAWKSRDCESTLPYVCKKYLNPTDHGVVEKDAWKYYATHCEPGWNPHNRNCYKLQKEKKTWNEALQSCQSNNSVLTDITSLAEVEFLVTLLGDENASETWIGLSSHKIPVSFEWSNGSSVTFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEETLFYLCKKTGLVLSDTESGCQKGWERHGKFCYKIDTVLRSFDHASSGYYCPPALITITSRFEQAFITSLISSVVKTKDTYFWIALQDQNNTGEYTWKTAGQQLEPVKYTHWNTRQPRYSGGCVVMRGRSHPGRWEVRDCRHFKAMSLCKQPVENREKTKQEEGWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWRQAEEFCEEFGAHLASFAHIEEENFVNELLHSKFNRTEERQFWIGFNKRNPLNAGSWEWSDGTPVVSSFLDNSYFGEDARNCAVYKANKTLLPSYCGSKREWICKIPRDVRPKVPPWYQYDAPWLFYQDAEYLFHISASEWSSFEFVCGWLRSDILTIHSAHEQEFIHSKIRALSKYGVNWWIGLREERASDEFRWRDGSPVIYQNWDKGKERSMGLNESQRCGFISSITGLWASEECSISMPSICKRKKVWVIEKKKDIPKQHGTCPKGWLYFDYKCLLLKIPEGPSDWKNWTSAQDFCVEEGGTLVAIENEVEQAFITMNLFGHTTNVWIGLQDDDYEKWLNGRPVSYSNWSPFDTKNIPNHNTTEVQKRIPLCGLLSNNPNFHFTGKWYFEDCREGYGFVCEKMQDASGHSINTSDMYPIPNTLEYGNRTYKIINANMTWYTALKTCLMHGAELASITDQYHQSFLTVILNRVGYAHWIGLFTEDNGLSFDWSDGTKSSFTFWKDDESSFLGDCVFADTSGRWSSTACESYLQGAICQVPTETRLSGRLELCSETSIPWIKFKSNCYSFSTVLESTSFEAAHEFCKKKGSNLLTIKDEAENSFLLEELLAFRSSVQMIWLNAQFDGDNETIKWFDGTPTDQSNWGIRKPEVYHFKPHLCVALRIPEGVWQLSSCQDKKGFICKMEADIHTVKKHPGKGPSHSVIPLTVALTLLVILAISTLSFCMYKHSHIIFGRLAQFRNPYYPSANFSTVHLEENILISDLEKNDQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
93	N-linked (GlcNAc...) asparagine	UniProt
454	N-linked (GlcNAc...) asparagine	UniProt
1057	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Acyl chain remodelling of PC	Bos taurus
Acyl chain remodelling of PE	Bos taurus
Acyl chain remodelling of PG	Bos taurus
Acyl chain remodelling of PI	Bos taurus
Acyl chain remodelling of PS	Bos taurus
Synthesis of PA	Bos taurus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements